Evidence map›Paper›PMID 38453993›Full record

ArticleScientific reports2024

Identification of microbial pathogens in Neolithic Scandinavian humans.

Nora Bergfeldt, Emrah Kırdök, Nikolay Oskolkov, Claudio Mirabello, Per Unneberg, Helena Malmström, Magdalena Fraser, Federico Sanchez-Quinto, Roger Jorgensen, Birgitte Skar and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nora BergfeldtCentre for Palaeogenetics, Stockholm University, Stockholm, Sweden. nora.bergfeldt@zoologi.su.se.
Emrah KırdökDepartment of Biotechnology, Faculty of Science, Mersin University, Mersin, Turkey.
Nikolay OskolkovScience for Life Laboratory, Department of Biology, National Bioinformatics Infrastructure Sweden, Lund University, Lund, Sweden.
Claudio MirabelloScience for Life Laboratory, Department of Physics, Chemistry and Biology, National Bioinformatics Infrastructure Sweden, Linköping University, Linköping, Sweden.
Per UnnebergScience for Life Laboratory, Department of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Uppsala University, Uppsala, Sweden.
Helena MalmströmHuman Evolution, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Magdalena FraserHuman Evolution, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Federico Sanchez-QuintoHuman Evolution, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Roger JorgensenTromsø University Museum, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Birgitte SkarDepartment of Archaeology and Cultural History, NTNU University Museum, Trondheim, Norway.
Kerstin LidénDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Mattias JakobssonHuman Evolution, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Jan StoråDepartment of Archaeology and Classical Studies, Stockholm University, Stockholm, Sweden.
Anders GötherströmCentre for Palaeogenetics, Stockholm University, Stockholm, Sweden.

Funding

Riksbankens Jubileumsfond P19.0740:1Riksbankens Jubileumsfond P21-0266Vetenskapsrådet 2017-02503Vetenskapsrådet 2019-00849
6 · The paper itself

Abstract

With the Neolithic transition, human lifestyle shifted from hunting and gathering to farming. This change altered subsistence patterns, cultural expression, and population structures as shown by the archaeological/zooarchaeological record, as well as by stable isotope and ancient DNA data. Here, we used metagenomic data to analyse if the transitions also impacted the microbiome composition in 25 Mesolithic and Neolithic hunter-gatherers and 13 Neolithic farmers from several Scandinavian Stone Age cultural contexts. Salmonella enterica, a bacterium that may have been the cause of death for the infected individuals, was found in two Neolithic samples from Battle Axe culture contexts. Several species of the bacterial genus Yersinia were found in Neolithic individuals from Funnel Beaker culture contexts as well as from later Neolithic context. Transmission of e.g. Y. enterocolitica may have been facilitated by the denser populations in agricultural contexts.

Indexed as

DNA, MitochondrialMicrobiotaYersiniaAgricultureEuropeHistory, AncientHumansDNA, Mitochondrial

Identifiers

PMID38453993
PMCPMC10920878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.