Evidence map›Paper›PMID 38453979›Full record

ArticleScientific reports2024

The model student: GPT-4 performance on graduate biomedical science exams.

Daniel Stribling, Yuxing Xia, Maha K Amer, Kiley S Graim, Connie J Mulligan, Rolf Renne

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  11. Large language models in biomedicine and health: current research landscape and future directions.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel StriblingDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, 32610, USA. ds@ufl.edu.ORCID http://orcid.org/0000-0002-0649-9506
Yuxing XiaDepartment of Neuroscience, Center for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0002-8415-8256
Maha K AmerDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, 32610, USA.
Kiley S GraimDepartment of Computer and Information Science and Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0002-4569-8444
Connie J MulliganUF Genetics Institute, University of Florida, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0002-4360-2402
Rolf RenneDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, 32610, USA. rrenne@ufl.edu.ORCID http://orcid.org/0000-0001-7391-8806

Funding

"Project 3" MHV68 IncRNA/miRNA interaction in latency and lympomagenesisP01CA214091 · NCI · UNIVERSITY OF FLORIDA · PI ERIK K FLEMINGTON · 2017 to 2026
$15.9M
Team-based Interdisciplinary Cancer Research Training ProgramT32CA257923 · NCI · UNIVERSITY OF FLORIDA · PI SIEMANN, DIETMAR W · 2021 to 2025
$1.2M
NCI NIH HHS P01 CA214091NCI NIH HHS T32 CA257923NIH HHS T32 CA257923
6 · The paper itself

Abstract

The GPT-4 large language model (LLM) and ChatGPT chatbot have emerged as accessible and capable tools for generating English-language text in a variety of formats. GPT-4 has previously performed well when applied to questions from multiple standardized examinations. However, further evaluation of trustworthiness and accuracy of GPT-4 responses across various knowledge domains is essential before its use as a reference resource. Here, we assess GPT-4 performance on nine graduate-level examinations in the biomedical sciences (seven blinded), finding that GPT-4 scores exceed the student average in seven of nine cases and exceed all student scores for four exams. GPT-4 performed very well on fill-in-the-blank, short-answer, and essay questions, and correctly answered several questions on figures sourced from published manuscripts. Conversely, GPT-4 performed poorly on questions with figures containing simulated data and those requiring a hand-drawn answer. Two GPT-4 answer-sets were flagged as plagiarism based on answer similarity and some model responses included detailed hallucinations. In addition to assessing GPT-4 performance, we discuss patterns and limitations in GPT-4 capabilities with the goal of informing design of future academic examinations in the chatbot era.

Indexed as

Education, GraduateHallucinationsHumansKnowledgeLanguageStudents

Identifiers

PMID38453979
PMCPMC10920673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.