Evidence map›Paper›PMID 38453057›Full record

ArticleVirus research2024

Molecular and biological characterization of a novel partitivirus from Talaromyces pinophilus.

Sidra Hassan, Urayama Syun-Ichi, Saba Shabeer, Tahseen Ali Kiran, Chien-Fu Wu, Hiromitsu Moriyama, Robert H A Coutts, Ioly Kotta Loizou, Atif Jamal

Open access · goldAbstract read
In one paragraph

Article in Virus research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Sidra HassanDepartment of Plant and Environmental Protection, PARC Institute of Advanced Studies in Agriculture (Affiliated with Quaid-i-Azam University), National Agricultural Research Centre, Islamabad 45500, Pakistan.
Urayama Syun-IchiLaboratory of Fungal Interaction and Molecular Biology (donated by IFO), Department of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan.
Saba ShabeerDepartment of Bioscience, COMSATS University, Islamabad 44000, Pakistan; Crop Diseases Research Institute (CDRI), National Agricultural Research Centre, Park Road, Islamabad 45500, Pakistan.
Tahseen Ali KiranCrop Diseases Research Institute (CDRI), National Agricultural Research Centre, Park Road, Islamabad 45500, Pakistan.
Chien-Fu WuLaboratory of Molecular and Cellular Biology, Department of Applied Biological Sciences, Tokyo University of Agriculture & Technology, 3-5-8, Saiwaicho, Fuchu, Tokyo 184-8509, Japan.
Hiromitsu MoriyamaLaboratory of Molecular and Cellular Biology, Department of Applied Biological Sciences, Tokyo University of Agriculture & Technology, 3-5-8, Saiwaicho, Fuchu, Tokyo 184-8509, Japan.
Robert H A CouttsDepartment of Clinical, Pharmaceutical & Biological Science, School of Life and Medical Sciences, University of Hertfordshire, AL10 9AB, Hatfield, United Kingdom.
Ioly Kotta LoizouDepartment of Clinical, Pharmaceutical & Biological Science, School of Life and Medical Sciences, University of Hertfordshire, AL10 9AB, Hatfield, United Kingdom; Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, SW7 2AZ, London, United Kingdom. Electronic address: i.kotta-loizou2@herts.ac.uk.
Atif JamalCrop Diseases Research Institute (CDRI), National Agricultural Research Centre, Park Road, Islamabad 45500, Pakistan. Electronic address: a.jamal@parc.gov.pk.
Pakistan Agricultural Research Council · PKTokyo University of Agriculture and Technology · JPUniversity of Hertfordshire · GBCOMSATS University Islamabad · PKQuaid-i-Azam University · PKUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Talaromyces spp. have a worldwide distribution, are ecologically diverse and have been isolated from numerous different substrates. Talaromyces spp. are considered biotechnologically important due to their ability to produce a range of enzymes and pigments. Talaromyces pinophilus, belonging to genus Talaromyces and family Trichocomaceae, is known for producing several important bioactive metabolites. Here we report the isolation and characterisation of a partitivirus from T. pinophilus which we have nominated Talaromyces pinophilus partitivirus-1 (TpPV-1). TpPV-1 possesses a genome consisting of three double stranded (ds) RNA segments i.e., dsRNAs1-3, 1824 bp, 1638 bp and 1451 bp respectively, which are encapsidated in icosahedral particles 35 nm in diameter. Both dsRNA1 and dsRNA2 contain a single open reading frame (ORF) encoding respectively a 572 amino acid (aa) protein of 65 kDa and a 504 aa protein of 50 kDa. The third segment (dsRNA3) is potentially a satellite RNA. Phylogenetic analysis revealed that the TpPV-1 belongs to the family Partitiviridae in the proposed genus Zetapartitivirus. TpPV-1 infection decreases the mycelial growth rate of the host fungus and alters pigmentation as indicated by time course experiments performed on a range of different solid media comparing virus-infected and virus-free isogenic lines. This is the first report of mycovirus infection in T. pinophilus and may provide insights into understanding the effect of the mycovirus on the production of enzymes and pigments by the host fungus.

Indexed as

Fungal VirusesRNA VirusesTalaromycesGenome, ViralOpen Reading FramesPhylogenyRNA, Double-StrandedRNA, ViralRNA, Double-StrandedRNA, ViralDouble-stranded RNAGrowthMetabolismPartitiviridaePigmentationSatellite RNATalaromyces pinophilusZetapartitivirus

Identifiers

PMID38453057
PMCPMC10982079
OpenAlexW4392672773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.