Evidence map›Paper›PMID 38452227›Full record

ArticleAmerican journal of respiratory and critical care medicine2024

Deep Learning-based Segmentation of Computed Tomography Scans Predicts Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis.

Muhunthan Thillai, Justin M Oldham, Alessandro Ruggiero, Fahdi Kanavati, Tom McLellan, Gauri Saini, Simon R Johnson, Francois-Xavier Ble, Adnan Azim, Kristoffer Ostridge and 4 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. A systematic review of the role of quantitative CT in the prognostication and disease monitoring of interstitial lung disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Review
  12. Article
  13. A multidimensional index with SpORespiratory research & clinical practice · 2026
    Article
  14. COVID-19 and Interstitial Lung Disease.Medicina (Kaunas, Lithuania) · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Radiomics and Artificial Intelligence in Pulmonary Fibrosis.Journal of imaging informatics in medicine · 2025
    Review
  19. Review
  20. A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Muhunthan ThillaiRoyal Papworth Hospital, Cambridge, United Kingdom.
Justin M OldhamDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4957-8869
Alessandro RuggieroRoyal Papworth Hospital, Cambridge, United Kingdom.
Fahdi KanavatiQureight Ltd., Cambridge, United Kingdom.
Tom McLellanRoyal Papworth Hospital, Cambridge, United Kingdom.
Gauri SainiTranslational Medical Sciences, National Institute for Health and Care Research Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Simon R JohnsonTranslational Medical Sciences, National Institute for Health and Care Research Biomedical Research Centre and Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0002-9837-2763
Francois-Xavier BleTranslational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
Adnan AzimTranslational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
Kristoffer OstridgeTranslational Science and Experimental Medicine.
Adam PlattTranslational Science and Experimental Medicine.
Maria BelvisiNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Toby M MaherNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0001-7192-9149
Philip L MolyneauxNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0003-1301-8800
Papworth Hospital · GBAstraZeneca (United Kingdom) · GBUniversity of Nottingham · GBAstraZeneca (Sweden) · SEEight19 (United Kingdom) · GBGuy's and St Thomas' NHS Foundation Trust · GBUniversity of Michigan · USUniversity of Southampton · GBUniversity of Southern California · US

Funding

Proteomic Profiling of Idiopathic Pulmonary Fibrosis Progression TrajectoryR01HL169166 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2023 to 2026
$2.7M
Prognostic Biomarker Development in Progressive Fibrosing Interstitial Lung DiseaseR01HL166290 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2024 to 2026
$2.2M
NHLBI NIH HHS R01 HL166290NHLBI NIH HHS R01 HL169166Qureight Ltd.
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Deep LearningDisease ProgressionIdiopathic Pulmonary FibrosisTomography, X-Ray ComputedAgedCohort StudiesFemaleHumansLungMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesUnited KingdomIPFmachine learning

Identifiers

PMID38452227
PMCPMC11351794
OpenAlexW4392543039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.