Evidence map›Paper›PMID 38452034›Full record

ArticlePloS one2024

A scoping review on the clinical effectiveness of Trans-Impedance Matrix (TIM) measurements in detecting extracochlear electrodes and tip fold overs in Cochlear Ltd devices.

Muhammed Ayas, Jameel Muzaffar, Daniele Borsetto, Susan Eitutis, Veronica Phillips, Yu Chuen Tam, Marina Salorio-Corbetto, Manohar L Bance

Open access · goldAbstract readScoping Review
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Trans-impedance matrix heatmap patterns in cochlear implant patients with different cochlear pathologies: meningitis, otosclerosis, and temporal bone fractures.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Sensitivity and Specificity of Intraoperative TransImpedance Matrix Recordings Compared With X-ray Imaging in Detecting Perimodiolar Cochlear Implant Tip Foldovers: A Multicenter Study.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2025
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Muhammed AyasCollege of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.ORCID 0000-0001-8373-7232
Jameel MuzaffarCambridge Hearing Group, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-3065-0269
Daniele BorsettoCambridge Hearing Group, University of Cambridge, Cambridge, United Kingdom.
Susan EitutisEmmeline Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Veronica PhillipsMedical Library, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.ORCID 0000-0002-4383-9434
Yu Chuen TamEmmeline Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Marina Salorio-CorbettoEmmeline Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Manohar L BanceCambridge Hearing Group, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtrusion of electrodes outside the cochlea and tip fold overs may lead to suboptimal outcomes in cochlear implant (CI) recipients. Intraoperative measures such as Trans-Impedance Matrix (TIM) measurements may enable clinicians to identify electrode malposition and direct surgeons to correctly place the electrode array during surgery.

objectivesTo assess the current literature on the effectiveness of TIM measurements in identifying extracochlear electrodes and tip fold overs.

methodsA scoping review of studies on TIM-based measurements were carried out using the Databases-Medline/PubMed, AMED, EMBASE, CINAHL and the Cochrane Library following PRISMA guidelines. Eleven full texts articles met the inclusion criteria. Only human studies pertaining to TIM as a tool used in CI were included in the review. Further, patient characteristics, electrode design, and TIM measurement outcomes were reported.

resultsTIM measurements were available for 550 implanted ears with the subjects age ranged between 9 months to 89 years. Abnormal TIM measurements were reported for 6.55% (36). Tip fold over was detected in 3.64% (20) of the cases, extracochlear electrodes in 1.45% (8), and 1.45% (8) were reported as buckling. Slim-modiolar electrode array designs were more common (54.71%) than pre-curved (23.34%) or lateral wall (21.95%) electrode array. Abnormal cochlear anatomy was reported for five ears (0.89%), with normal cochlear anatomy for all other patients.

conclusionTIM measurement is a promising tool for the intraoperative detection of electrode malposition. TIM measurement has a potential to replace intraoperative imaging in future. Though, TIM measurement is in its early stages of clinical utility, intuitive normative data sets coupled with standardised criteria for detection of abnormal electrode positioning would enhance its sensitivity.

Indexed as

Cochlear ImplantationCochlear ImplantsCochleaElectric ImpedanceElectrodes, ImplantedHumansTreatment Outcome

Identifiers

PMID38452034
PMCPMC10919746
OpenAlexW4392564100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.