Evidence map›Paper›PMID 38451411›Full record

ReviewClinical journal of gastroenterology2024

Simultaneous gastric, pancreatic, and renal metastasis from poorly differentiated hepatocellular carcinoma.

Manabu Uchikoshi, Takayoshi Ito, Yoko Nakajima, Ikuya Sugiura, Shoujirou Uozumi, Yuu Shimozuma, Masashi Sakaki, Yasuyuki Ohira, Toshiko Yamochi, Hitoshi Yoshida

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PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Manabu UchikoshiDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan. uchii@med.showa-u.ac.jp.ORCID http://orcid.org/0009-0006-6306-1582
Takayoshi ItoDigestive Diseases Center, Showa University Koto Toyosu Hospital, 5-1-38 Toyosu, Kotoku, Tokyo, 135-8577, Japan.
Yoko NakajimaDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Ikuya SugiuraDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Shoujirou UozumiDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Yuu ShimozumaDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Masashi SakakiDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Yasuyuki OhiraDepartment of Pathology and Laboratory Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Toshiko YamochiDepartment of Pathology and Laboratory Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Hitoshi YoshidaDivision of Gastroenterology, Department of Internal Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawaku, Tokyo, 142-8666, Japan.
Showa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common extrahepatic metastasis sites of hepatocellular carcinoma (HCC) are the lungs, adrenal glands, and bones. Herein, we report a rare case of metastatic gastric, pancreatic, and renal tumors from HCC simultaneously, and review the relevant literature. A 75-year-old woman presented with right hypochondralgia, appetite loss, and weight loss. Computed tomography revealed suspected metastatic liver, lung, and renal tumors. A blood test revealed a leukocyte count of 26,210/μL and a high inflammatory reaction. As sepsis was suspected, the patient was referred to our hospital. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging revealed a hypovascular liver tumor that was suspected to be metastatic. Upper gastrointestinal endoscopy revealed two suspected metastatic gastric tumors. Liver and gastric tumor biopsies revealed poor carcinoma in both. The patient's condition gradually worsened and she died on day 8 of the illness. Based on autopsy findings, the patient was finally diagnosed with metastatic gastric and renal tumors originating from HCC. Additionally, a metastatic pancreatic tumor originating from the HCC was identified during autopsy. The pathological diagnosis of the pulmonary lesion was primary lung adenocarcinoma. In conclusion, HCC should be suspected in cases with multiple metastases of unknown primary lesions.

Indexed as

Carcinoma, HepatocellularKidney NeoplasmsLiver NeoplasmsPancreatic NeoplasmsStomach NeoplasmsAgedFatal OutcomeFemaleHumansLung NeoplasmsMagnetic Resonance ImagingTomography, X-Ray ComputedAdenocarcinomaExtrahepatic metastasisHepatocellular carcinoma

Identifiers

PMID38451411
PMCPMC11127805
OpenAlexW4392563786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.