ArticleEuropean journal of nutrition2024
Whole-grain intake in mid-life and healthy ageing in the Danish Diet, Cancer and Health cohort.
Article in European journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Effectiveness of whole grain to body weight and cardiometabolic risk in adults with obesity: a parallel randomised controlled trial.Frontiers in nutrition · 2026Article
- Ultra-processed food consumption and risk of dementia and Alzheimer's disease: The Framingham Heart Study.The journal of prevention of Alzheimer's disease · 2025Article
- Associations of the planetary health diet index (PHDI) with asthma: the mediating role of body mass index.BMC public health · 2024Article
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Authors and funding
7 authors.
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Abstract
purposeGrowing elderly populations worldwide have sparked interest in factors promoting healthy aging. Diet and other lifestyle patterns are key factors for healthy ageing; however, evidence is sparse for specific dietary guidelines that are easily implemented in everyday life. Whole grains constitute specific dietary components with unexplored potential in healthy ageing.
methodsWe applied an illness-death multistate model to assess the association between whole-grain intake and life expectancy, both with and without disease, over a 20-year period. Healthy ageing was defined as absence of cancer, ischemic heart disease, stroke, type 2 diabetes, asthma, chronic obstructive pulmonary disease, and dementia during follow-up.
resultsBased on information from 22,606 men and 25,468 women in the Danish Diet, Cancer and Health cohort, followed for an average of 13.8 and 17.5 years, respectively, a doubling in whole-grain intake was associated with 0.43 (95% CI: 0.33-0.52) and 0.15 (0.06-0.24) additional years without disease for men and women, respectively. Comparing the highest and lowest quartiles of whole-grain intake, with a special emphasis on men, we found that those with the highest intake lived, on average, one year longer without disease compared to those with the lowest intake. Additionally, although a high intake of whole grains yielded longer life expectancy, the duration of living with disease was shorter.
conclusionIntake of whole grains in mid-life was associated with healthy ageing looking 20 years ahead.
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