Evidence map›Paper›PMID 38451282›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2024

Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na

Chi-Min Du, Wohn-Jenn Leu, Yi-Huei Jiang, She-Hung Chan, Ih-Sheng Chen, Hsun-Shuo Chang, Lih-Ching Hsu, Jui-Ling Hsu, Jih-Hwa Guh

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chi-Min DuSchool of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan.
Wohn-Jenn LeuSchool of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan.
Yi-Huei JiangSchool of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan.
She-Hung ChanDepartment of Cosmetic Science, Providence University, 200, Sec. 7, Taiwan Boulevard, Shalu Dist, Taichung, 43301, Taiwan.
Ih-Sheng ChenSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Taiwan, Kaohsiung, Taiwan.
Hsun-Shuo ChangSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Taiwan, Kaohsiung, Taiwan.
Lih-Ching HsuSchool of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan.
Jui-Ling HsuSchool of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan. jlhsu@mail.cgust.edu.tw.
Jih-Hwa GuhSchool of Pharmacy, National Taiwan University, No. 33, Linsen S. Rd., Zhongzheng Dist, Taipei, 100, Taiwan. jhguh@ntu.edu.tw.
National Taiwan University · TWKaohsiung Medical University · TWProvidence University · TW

Funding

National Science and Technology Council NSTC 110-2320-B-002-031-MY3
6 · The paper itself

Abstract

The treatment of non-small cell lung cancer (NSCLC) is known as a significant level of unmet medical need in spite of the progress in targeted therapy and personalized therapy. Overexpression of the Na

Indexed as

ApoptosisCarcinoma, Non-Small-Cell LungCardenolidesGefitinibLung NeoplasmsSodium-Potassium-Exchanging ATPaseA549 CellsAntineoplastic AgentsCell Line, TumorDrug SynergismHumansAntineoplastic AgentsCardenolidesGefitinibSodium-Potassium-Exchanging ATPaseBax cleavageGefitinibNa+/K+-ATPaseNon-small cell lung cancerTubulin acetylation

Identifiers

PMID38451282
OpenAlexW4392560114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.