ArticleRadiology. Cardiothoracic imaging2024
Associations between 3D-based Left Atrial Volumetric and Blood Flow Parameters in a Single-Site Cohort of the Multi-Ethnic Study of Atherosclerosis.
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Article in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1citing papers in PubMed
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1 citing paper in PubMed, 2 citations in OpenAlex.
- Left Atrial Function and Volume Associations with Hemodynamics in a Representative Aged Cohort: Unlocking New Insights.Radiology. Cardiothoracic imaging · 2024Article
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Authors and funding
12 authors at 3 institutions in 2 countries.
Maurice PradellaFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0003-2449-7835
Justin J BarabooFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).
Anthony MarounFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0002-6673-6008
Sophia Z LiuFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0003-3230-8774
Amanda L DiCarloFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0001-7587-6021
Stanley H ChuFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).
Julia M HwangFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).
Mitchell A CollinsFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0003-2975-3228
Rod PassmanFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).
Susan R HeckbertFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0002-7100-512X
Philip GreenlandFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0002-6327-2439
Michael MarklFrom the Department of Radiology (M.P., J.J.B., A.M., S.Z.L., A.L.D., S.H.C., J.M.H., M.A.C., M.M.), Department of Medicine, Division of Cardiology (R.P., P.G.), and Department of Preventive Medicine (P.G.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland (M.P.); and Department of Epidemiology, University of Washington, Seattle, Wash (S.R.H.).ORCID 0000-0002-7686-1128
University Hospital of Basel · CHNorthwestern University · USUniversity of Basel · CH
Funding
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MWake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MTask Area A Core Study Operations.Task Area A shall encompass annual follow-up of cohort members, clinical endpoints ascertainment, study coordination activities, maintenance of the database and biosp75N92020D00001 · NHLBI · UNIVERSITY OF WASHINGTON · PI MCCLELLAND, ROBYN LEAGH · 2020 to 2025
$17.2MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1MTO EXERCISE OPTION PERIOD ONE (1) FOR TASK AREA A - MESA CORE OPERATIONS, FIELD CENTER.75N92020D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI SIEGEL, JONATHAN H · 2020 to 2025
$4.5MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI PANKOW, JAMES S · 2020 to 2025
$4.4MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00003 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POST, WENDY S · 2020 to 2025
$3.8MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00007 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BERTONI, ALAIN GERALD · 2020 to 2025
$3.5MTask Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00002 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN J · 2020 to 2025
$3.4MCigarette Smoke and Susceptibility to Influenza InfectionR01HL095163 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, NOAH, TERRY L · 2009 to 2013
$2.0MAdjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3MNCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS F31 HL165915NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169
Abstract
Purpose To investigate associations between left atrial volume (LAV) and function with impaired three-dimensional hemodynamics from four-dimensional flow MRI. Materials and Methods A subcohort of participants from the Multi-Ethnic Study of Atherosclerosis from Northwestern University underwent prospective 1.5-T cardiac MRI including whole-heart four-dimensional flow and short-axis cine imaging between 2019 and 2020. Four-dimensional flow MRI analysis included manual three-dimensional segmentations of the LA and LA appendage (LAA), which were used to quantify LA and LAA peak velocity and blood stasis (% voxels < 0.1 m/sec). Short-axis cine data were used to delineate LA contours on all cardiac time points, and the resulting three-dimensional-based LAVs were extracted for calculation of LA emptying fractions (LAEF
Indexed as
AtherosclerosisAtrial AppendageAgedFemaleHeart AtriaHemodynamicsHumansMaleProspective Studies4D Flow MRIAtherosclerosisLeft Atrial Blood FlowLeft Atrial Volume
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