Evidence map›Paper›PMID 38451007›Full record

Trial reportBrain and behavior2024

The effects of standard and modified LSVT BIG therapy protocols on balance and gait in Parkinson's disease: A randomized controlled trial.

Sefa Eldemir, Kader Eldemir, Fettah Saygili, Cagla Ozkul, Rezzak Yilmaz, Muhittin Cenk Akbostancı, Arzu Guclu-Gunduz

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Sefa EldemirDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Sivas Cumhuriyet University, Sivas, Türkiye.ORCID 0000-0002-2122-5706
Kader EldemirDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ordu University, Ordu, Türkiye.
Fettah SaygiliDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Aydın Adnan Menderes University, Aydın, Türkiye.
Cagla OzkulDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Türkiye.
Rezzak YilmazDepartment of Neurology and Ankara University Brain Research Center, Ankara University, School of Medicine, Ankara, Türkiye.
Muhittin Cenk AkbostancıDepartment of Neurology and Ankara University Brain Research Center, Ankara University, School of Medicine, Ankara, Türkiye.
Arzu Guclu-GunduzDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Türkiye.
Ankara University · TRGazi University · TRAdnan Menderes University · TROrdu University · TRSivas Cumhuriyet Üniversitesi · TR

Funding

This research was supported by Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (TUBITAK, Scientific and Technical Research Council of Turkey) for open access.
6 · The paper itself

Abstract

backgroundLee Silverman voice treatment (LSVT) BIG is an exercise program developed for patients with Parkinson's disease (PwPD), consisting of sets of exercises performed for 4 consecutive days a week for 4 weeks. However, the standard protocol suggests a treatment frequency difficult to follow for most patients who have difficulties reaching rehabilitation clinics. Our aim was to compare the standard LSVT BIG protocol with a modified LSVT (m-LSVT) BIG protocol (twice a week in the clinic for 4 weeks and twice a week at home for 4 weeks).

methodsIn this randomized controlled trial, 16 PwPD (aged 18-80 years, Hoehn and Yahr stages I-III) were recruited into two groups. The LSVT group received standard LSVT BIG training (four times per week for 4 weeks at the clinic). The other group was given m-LSVT BIG exercises, but unlike the LSVT group, the m-LSVT group exercised twice a week at the clinic and twice a week at home for 4 weeks. The Berg Balance Scale was used to assess functional balance. Biodex Balance System was used to assess laboratory balance measures. Timed Up and Go test and G-Walk sensor system were used to assess functional mobility and spatiotemporal gait analysis.

resultsSignificant group-by-time interactions on the eyes open-firm surface score of the modified clinical test of sensory integration of balance (F = 10.138, p = .007) and gait cycle symmetry index (F = 10.470, p = .010) were found to be in favor of the LSVT group. Additionally, post hoc analyses revealed that both groups significantly improved postural stability, gait speed, motor symptoms, and functional mobility (p < .05).

conclusionThe results revealed the beneficial effects of the modified protocol on balance and gait in PwPD, as well as the superiority of the standard LSVT BIG protocol. The m-LSVT BIG protocol may be an effective intervention method, especially for PwPD who have difficulty adapting to the treatment frequency of the standard protocol.

Indexed as

Parkinson DiseaseAdolescentAdultAgedAged, 80 and overExercise TherapyGaitHumansMiddle AgedPostural BalanceTime and Motion StudiesYoung AdultbalanceLSVT BIGParkinson's diseasephysiotherapy

Identifiers

PMID38451007
PMCPMC10918598
OpenAlexW4392553513

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.