Evidence map›Paper›PMID 38450712›Full record

ArticleJournal of the American Geriatrics Society2024

Individualized prediction of critical illness in older adults: Validation of an elders risk assessment model.

Svetlana Herasevich, Sarah A Minteer, Christopher L Boswell, Andrew C Hanson, Yue Dong, Ognjen Gajic, Amelia K Barwise

Open access · greenAbstract readValidation Study
In one paragraph

Article in Journal of the American Geriatrics Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Svetlana HerasevichDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Sarah A MinteerRobert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA.
Christopher L BoswellDepartment of Family Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Andrew C HansonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Yue DongDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Ognjen GajicDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Amelia K BarwiseDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · USWinnMed · USMayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Kogod Center for Aging at Mayo ClinicNCATS NIH HHS UL1 TR002377NCATS NIH HHS UL1TR002377
6 · The paper itself

Abstract

backgroundThe electronic health record (EHR) presents new opportunities for the timely identification of patients at high risk of critical illness and the implementation of preventive strategies. This study aims to externally validate an EHR-based Elders Risk Assessment (ERA) score to identify older patients at high risk of future critical illness during a primary care visit.

methodsThis historical cohort study included patients aged ≥65 years who had primary care visits at Mayo Clinic Rochester, MN, between July 2019 and December 2021. The ERA score at the time of the primary care visit was used to predict critical illness, defined as death or ICU admission within 1 year of the visit.

resultsA total of 12,885 patients were included in the analysis. The median age at the time of the primary care visit was 75 years, with 44.6% being male. 93.7% of participants were White, and 64.2% were married. The median (25th, 75th percentile) ERA score was 4 (0, 9). 11.3% of study participants were admitted to the ICU or died within 1 year of the visit. The ERA score predicted critical illness within 1 year of a primary care visit with an area under the receiver operating characteristic curve of 0.84 (95% CI 0.83-0.85), which indicates good discrimination. An ERA score of 9 was identified as optimal for implementing and testing potential preventive strategies, with the odds ratio of having the primary outcome in patients with ERA score ≥9 being 11.33 (95%CI 9.98-12.87).

conclusionsThis simple EHR-based risk assessment model can predict critical illness within 1 year of primary care visits in older patients. The findings of this study can serve as a basis for testing and implementation of preventive strategies to promote the well-being of older adults at risk of critical illness and its consequences.

Indexed as

Critical IllnessElectronic Health RecordsGeriatric AssessmentAgedAged, 80 and overCohort StudiesFemaleHospitalizationHumansIntensive Care UnitsMalePrimary Health CareRisk Assessmentcommunity‐based preventioncritical illnesselders risk assessmentmortalityrisk predictionscore

Identifiers

PMID38450712
PMCPMC11187675
OpenAlexW4392560698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.