Evidence map›Paper›PMID 38450242›Full record

ArticleFrontiers in nutrition2024

Tea intake and total body bone mineral density of all ages: a Mendelian randomization analysis.

Chen Xing, Yanrong Tan, Wentao Ni

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Chen XingDepartment of Gastroenterology, Institute of Digestive Diseases of PLA, The First Affiliated Hospital (Southwest Hospital), Army Medical University (Third Military Medical University), Chongqing, China.
Yanrong TanDepartment of Gastroenterology, Institute of Digestive Diseases of PLA, The First Affiliated Hospital (Southwest Hospital), Army Medical University (Third Military Medical University), Chongqing, China.
Wentao NiBeijing Key Laboratory of Genome and Precision Medicine Technologies, Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Southwest Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is increasing evidence indicating that tea intake affects bone mineral density levels; however, the causality between tea intake and bone mineral density is inconclusive. This study aimed to assess the causal relationship between tea intake and total body bone mineral density (TB-BMD) through two-sample Mendelian randomization (MR) analysis. Methods: We conducted a two-sample MR approach to estimate the potential causal effects of tea intake on TB-BMD at all ages in a European population. The analyses were performed using summary statistics obtained for single-nucleotide polymorphisms (SNPs), identified from a genome-wide association meta-analysis of tea intake ( Results: The MR analysis revealed that genetically determined tea intake exerts a causal impact on TB-BMD, with an odds ratio (OR) of 1.204 (95% CI: 1.062-1.366, Conclusion: The findings of this study support the evidence that tea consumption increases bone density and reduces the risk of osteoporosis in the age group of 45-60 years within the European population.

Indexed as

causalitygenome-wide association study (GWAS)Mendelian randomization (MR) analysistea intaketotal body bone mineral density (TB-BMD)

Identifiers

PMID38450242
PMCPMC10915007
OpenAlexW4392002682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.