Evidence map›Paper›PMID 38450221›Full record

ArticleFrontiers in human neuroscience2024

Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements.

Kara A Johnson, Nico U F Dosenbach, Evan M Gordon, Cristin G Welle, Kevin B Wilkins, Helen M Bronte-Stewart, Valerie Voon, Takashi Morishita, Yuki Sakai, Amanda R Merner and 32 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 8 countries.

Kara A JohnsonNorman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Nico U F DosenbachDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Evan M GordonDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Cristin G WelleDepartment of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, CO, United States.
Kevin B WilkinsDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, United States.
Helen M Bronte-StewartDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, United States.
Valerie VoonDepartment of Psychiatry, University of Cambridge, Cambridge, United Kingdom.
Takashi MorishitaDepartment of Neurosurgery, Fukuoka University Faculty of Medicine, Fukuoka, Japan.
Yuki SakaiATR Brain Information Communication Research Laboratory Group, Kyoto, Japan.
Amanda R MernerCenter for Bioethics, Harvard Medical School, Boston, MA, United States.
Gabriel Lázaro-MuñozCenter for Bioethics, Harvard Medical School, Boston, MA, United States.
Theresa WilliamsonDepartment of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States.
Andreas HornDepartment of Neurology, Center for Brain Circuit Therapeutics, Harvard Medical School, Brigham & Women's Hospital, Boston, MA, United States.
Ro'ee GilronRune Labs, San Francisco, CA, United States.
Jonathan O'KeeffeMachine Medicine, London, United Kingdom.
Aryn H GittisBiological Sciences and Center for Neural Basis of Cognition, Carnegie Mellon University, Pittsburgh, PA, United States.
Wolf-Julian NeumannMovement Disorder and Neuromodulation Unit, Department of Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt- Universität zu Berlin, Berlin, Germany.
Simon LittleDepartment of Neurological Surgery, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Nicole R ProvenzaDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, United States.
Sameer A ShethDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, United States.
Alfonso FasanoEdmond J. Safra Program in Parkinson's Disease, Division of Neurology, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network (UHN), University of Toronto, Toronto, ON, Canada.
Abbey B Holt-BeckerRestorative Therapies Group Implantables, Research, and Core Technology, Medtronic Inc., Minneapolis, MN, United States.
Robert S RaikeRestorative Therapies Group Implantables, Research, and Core Technology, Medtronic Inc., Minneapolis, MN, United States.
Lisa MooreBoston Scientific Neuromodulation Corporation, Valencia, CA, United States.
Yagna J PathakNeuromodulation Division, Abbott, Plano, TX, United States.
David GreeneNeuroPace, Inc., Mountain View, CA, United States.
Sara MarcegliaDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.
Lothar KrinkeNewronika SPA, Milan, Italy.
Huiling TanMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Hagai BergmanEdmond and Lily Safar Center (ELSC) for Brain Research and Department of Medical Neurobiology (Physiology), Institute of Medical Research Israel-Canada, Hebrew University of Jerusalem, Jerusalem, Israel.
Monika Pötter-NergerDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bomin SunDepartment of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Laura Y CabreraNeuroethics, Department of Engineering Science and Mechanics, Philosophy, and Bioethics, and the Rock Ethics Institute, Pennsylvania State University, State College, PA, United States.
Cameron C McIntyreDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Noam HarelDepartment of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States.
Helen S MaybergDepartment of Neurology, Neurosurgery, Psychiatry, and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Andrew D KrystalDepartments of Psychiatry and Behavioral Science and Neurology, University of California, San Francisco, San Francisco, CA, United States.
Nader PouratianDepartment of Neurological Surgery, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Philip A StarrDepartment of Neurological Surgery, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Kelly D FooteNorman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Michael S OkunNorman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
Joshua K WongNorman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
University of Florida · USUniversity of California, San Francisco · USBaylor College of Medicine · USHarvard University · USMedtronic (United States) · USStanford University · USWashington University in St. Louis · USAbbott (United States) · USBoston Scientific (United States) · USBrigham and Women's Hospital · USCenter for the Neural Basis of Cognition · USCharité - Universitätsmedizin Berlin · DEDuke University · USFukuoka University · JPHebrew University of Jerusalem · ILIcahn School of Medicine at Mount Sinai · USKyoto Prefectural University of Medicine · JPMassachusetts General Hospital · USNeurological Surgery · USNeuroPace (United States) · US

Funding

BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)UM1NS132358 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Suzanne N Haber, Elizabeth M. C. Hillman · 2023 to 2026
$17.5M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Jan Zimmermann · 2019 to 2026
$11.7M
Understanding Circuit Dynamics in Parkinson's Disease using Real-Time Neural ControlP50NS123109 · NINDS · UNIVERSITY OF MINNESOTA · PI AMAN, JOSHUA E · 2021 to 2025
$11.3M
Identification of outcome-based sub-populations using deep phenotyping and precision functional mapping across ADHD and ASDR01MH096773 · NIMH · UNIVERSITY OF MINNESOTA · PI DOSENBACH, NICO, FAIR, DAMIEN A · 2012 to 2024
$9.4M
Deep brain stimulation for depression using directional current steering an individualized network targetingUH3NS103549 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOODMAN, WAYNE K, POURATIAN, NADER · 2017 to 2025
$8.7M
Electrophysiological Biomarkers to Optimize DBS for DepressionUH3NS103550 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MAYBERG, HELEN S, RIVA-POSSE, PATRICIO · 2017 to 2023
$7.7M
Motion-robust brain MRI for infantsR44MH124567 · NIMH · TURING MEDICAL TECHNOLOGIES INC · PI BERTOLERO, MAXWELL, FAIR, DAMIEN A · 2020 to 2023
$7.3M
Using human brain connectivity to identify the causal neuroanatomical substrate of depression symptomsR01MH113929 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL D FOX · 2017 to 2026
$6.9M
Visual biofeedback to reduce head motion during MRI scansR44MH122066 · NIMH · TURING MEDICAL TECHNOLOGIES INC · PI BRUENER, KEN, FAIR, DAMIEN A · 2019 to 2022
$6.2M
Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait using Neural and Kinematic FeedbackUH3NS107709 · NINDS · STANFORD UNIVERSITY · PI BRONTE-STEWART, HELEN · 2019 to 2023
$6.1M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
Solving the MRI motion problem with Framewise Integrated Real-Time MRI Monitoring (FIRMM) softwareR44MH121276 · NIMH · TURING MEDICAL TECHNOLOGIES INC · PI FAIR, DAMIEN A, ROTHNEY, MEGAN PEARL · 2020 to 2023
$5.4M
NCATS NIH HHS KL2 TR001429NIBIB NIH HHS P41 EB027061NIH HHS S10 OD025256NIMH NIH HHS R01 MH096773NIMH NIH HHS R01 MH113929NIMH NIH HHS R01 MH130666NIMH NIH HHS R01 MH133657NIMH NIH HHS R44 MH121276NIMH NIH HHS R44 MH122066NIMH NIH HHS R44 MH124567NIMH NIH HHS RF1 MH117802NINDS NIH HHS K23 NS088590NINDS NIH HHS K23 NS120037NINDS NIH HHS P50 NS123109NINDS NIH HHS R01 NS081118NINDS NIH HHS R01 NS090913NINDS NIH HHS R01 NS096008NINDS NIH HHS R01 NS097782NINDS NIH HHS R01 NS113746NINDS NIH HHS R01 NS115975NINDS NIH HHS R01 NS127892NINDS NIH HHS R01 NS131405NINDS NIH HHS R25 NS108939NINDS NIH HHS R44 NS129521NINDS NIH HHS U01 NS119562NINDS NIH HHS UG3 NS128150NINDS NIH HHS UH3 NS103549NINDS NIH HHS UH3 NS103550NINDS NIH HHS UH3 NS107709NINDS NIH HHS UH3 NS119844NINDS NIH HHS UM1 NS132358NINR NIH HHS R01 NR014852Wellcome Trust
6 · The paper itself

Abstract

The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9-11, 2023 in Gainesville, Florida with the theme of "Pushing the Forefront of Neuromodulation". The keynote speaker was Dr. Nico Dosenbach from Washington University in St. Louis, Missouri. He presented his research recently published in Nature inn a collaboration with Dr. Evan Gordon to identify and characterize the somato-cognitive action network (SCAN), which has redefined the motor homunculus and has led to new hypotheses about the integrative networks underpinning therapeutic DBS. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers, and researchers (from industry and academia) can freely discuss current and emerging DBS technologies, as well as logistical and ethical issues facing the field. The group estimated that globally more than 263,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. This year's meeting was focused on advances in the following areas: cutting-edge translational neuromodulation, cutting-edge physiology, advances in neuromodulation from Europe and Asia, neuroethical dilemmas, artificial intelligence and computational modeling, time scales in DBS for mood disorders, and advances in future neuromodulation devices.

Indexed as

adaptive DBSartificial intelligencedeep brain stimulation (DBS)epilepsyinterventional psychiatryneuroethicsoptogeneticsParkinson's disease

Identifiers

PMID38450221
PMCPMC10915873
OpenAlexW4392018844

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.