Evidence map›Paper›PMID 38450055›Full record

ReviewFrontiers in pharmacology2023

Lung cancer, comorbidities, and medication: the infernal trio.

Hélène Pluchart, Sébastien Chanoine, Denis Moro-Sibilot, Christos Chouaid, Gil Frey, Julie Villa, Bruno Degano, Matteo Giaj Levra, Pierrick Bedouch, Anne-Claire Toffart

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Hélène PluchartPôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, La Tronche, France.
Sébastien ChanoinePôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, La Tronche, France.
Denis Moro-SibilotUniversité Grenoble Alpes, Grenoble, France.
Christos ChouaidService de Pneumologie, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
Gil FreyService de Chirurgie Thoracique, Vasculaire et Endocrinienne, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.
Julie VillaService de Radiothérapie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.
Bruno DeganoUniversité Grenoble Alpes, Grenoble, France.
Matteo Giaj LevraInstitut pour l'Avancée des Biosciences, UGA/INSERM U1209/CNRS 5309, Université Grenoble Alpes, La Tronche, France.
Pierrick BedouchPôle Pharmacie, Centre Hospitalier Universitaire Grenoble Alpes, La Tronche, France.
Anne-Claire ToffartUniversité Grenoble Alpes, Grenoble, France.
Centre Hospitalier Universitaire de Grenoble · FRUniversité Grenoble Alpes · FRCentre National de la Recherche Scientifique · FRHôpital Intercommunal de Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most patients with lung cancer are smokers and are of advanced age. They are therefore at high risk of having age- and lifestyle-related comorbidities. These comorbidities are subject to treatment or even polypharmacy. There is growing evidence of a link between lung cancer, comorbidities and medications. The relationships between these entities are complex. The presence of comorbidities and their treatments influence the time of cancer diagnosis, as well as the diagnostic and treatment strategy. On the other hand, cancer treatment may have an impact on the patient's comorbidities such as renal failure, pneumonitis or endocrinopathies. This review highlights how some comorbidities may have an impact on lung cancer presentation and may require treatment adjustments. Reciprocal influences between the treatment of comorbidities and anticancer therapy will also be discussed.

Indexed as

comorbiditiesdrug-drug interactionlung cancerpolypharmacysurvival

Identifiers

PMID38450055
PMCPMC10916800
OpenAlexW4391994857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.