Evidence map›Paper›PMID 38450040›Full record

ReviewNarra J2023

Monkeypox virus infection and myocarditis: A review of current evidence and possible pathogenesis.

Sirwan K Ahmed, Eman A Dabou, Shaimaa Abdelsamad, Mona G Mohamed, Deepak Chandran, Sandip Chakraborty, Talha B Emran, Kuldeep Dhama

Open access · diamondAbstract readReview
In one paragraph

Review in Narra J, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Rethinking mpox: epidemiology, clinical variants, diagnosis, and response.Osong public health and research perspectives · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Mpox Virus as a Global Public Health Emergency: A Scoping Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Cardiac Involvement in Monkeypox Outbreak.Discoveries (Craiova, Romania)
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Sirwan K AhmedDepartment of Pediatrics, Rania Pediatric and Maternity Teaching Hospital, Rania, Iraq.
Eman A DabouRAK College of Nursing, RAK Medical and Health Sciences University, Ras Al Khiamah, United Arab Emirates.
Shaimaa AbdelsamadRAK College of Nursing, RAK Medical and Health Sciences University, Ras Al Khiamah, United Arab Emirates.
Mona G MohamedRAK College of Nursing, RAK Medical and Health Sciences University, Ras Al Khiamah, United Arab Emirates.
Deepak ChandranDepartment of Veterinary Sciences and Animal Husbandry, Amrita School of Agricultural Sciences, Amrita Vishwa Vidyapeetham University, Coimbatore, India.
Sandip ChakrabortyDepartment of Veterinary Microbiology, College of Veterinary Sciences and Animal Husbandry, R.K. Nagar, West Tripura, India.
Talha B EmranDepartment of Pharmacy, BGC Trust University, Chittagong, Bangladesh.
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, India.
Ras al-Khaimah Medical and Health Sciences University · AEAmrita Vishwa Vidyapeetham · INDaffodil International University · BDIndian Veterinary Research Institute · INUniversity of Raparin · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent spread of the monkeypox virus (MPXV), causing monkeypox (mpox), to non-endemic areas, and the atypical and unusual clinical manifestations observed during its 2022 outbreak has focused international interest on the clinical features of the disease. Mpox is usually a self-limiting disease with mild symptoms with common manifestations, including fever and skin lesions; however, severe manifestations could occur in some vulnerable groups (children and those with impaired immune systems) and may present multisystem complications and fatal outcomes. In most cases, a fever is the first sign of disease, followed by the development of various inflammatory lesions on the skin, such as vesiculopustular rashes and ulcers. Pneumonitis, encephalitis, keratitis, secondary bacterial infections, acute kidney injury, and myocarditis are all possible outcomes of the infection. Myocarditis has been reported to be caused by orthopoxviruses, and it is a serious condition of which its pathophysiology is little understood. Recent reports have indicated myocarditis with cardiac involvement as a possible atypical and unusual consequence of the MPXV infection during present outbreak. This review provides an overview of the clinical manifestations of mpox with a special focus on its effects on the heart, including myocarditis. The evidence of the myocarditis in mpox patients and its possible pathogenesis are discussed.

Indexed as

Monkeypoxmpoxmyocarditisoutbreakpathogenesis

Identifiers

PMID38450040
PMCPMC10914025
OpenAlexW4366598535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.