Evidence map›Paper›PMID 38449772›Full record

ReviewJournal of clinical & translational endocrinology2024

GLP-1 receptor agonists: A novel pharmacotherapy for binge eating (Binge eating disorder and bulimia nervosa)? A systematic review.

Laurence Aoun, Shaza Almardini, Fares Saliba, Fadi Haddadin, Omar Mourad, Jennifer Jdaidani, Zeina Morcos, Ibrahim Al Saidi, Elie Bou Sanayeh, Saliba Saliba and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical & translational endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
27.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Hypothalamus-liver talks: whispers in the language of metabolism.Reviews in endocrine & metabolic disorders · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Observational
  18. Disordered eating and type 2 diabetes: The case for T2DE.Diabetic medicine : a journal of the British Diabetic Association · 2026
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Laurence AounDepartment of Internal Medicine, Staten Island University Hospital, United States.
Shaza AlmardiniDepartment of Internal Medicine, Staten Island University Hospital, United States.
Fares SalibaDepartment of Internal Medicine, Staten Island University Hospital, United States.
Fadi HaddadinDepartment of Internal Medicine, Staten Island University Hospital, United States.
Omar MouradDepartment of Internal Medicine, Staten Island University Hospital, United States.
Jennifer JdaidaniDepartment of Internal Medicine, Staten Island University Hospital, United States.
Zeina MorcosDepartment of Internal Medicine, Staten Island University Hospital, United States.
Ibrahim Al SaidiDepartment of Internal Medicine, Staten Island University Hospital, United States.
Elie Bou SanayehDepartment of Internal Medicine, Staten Island University Hospital, United States.
Saliba SalibaDepartment of Physiology, Mcgill University, United States.
Michel AlmardiniFaculty of Medicine, American University of Beirut Medical Center, Lebanon.
Julie ZaidanEndocrinology, Diabetes and Metabolism, Staten Island University Hospital, United States.
Staten Island University Hospital · USAmerican University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Systematically review evidence on using GLP-1RAs for reducing BEB in BED and BN. Methods: Comprehensive literature search (PubMed and Google Scholar) conducted for studies evaluating GLP-1Ras for BEB. Extracted data on study characteristics, efficacy, and safety. Results: Studies show that GLP-1RAs (liraglutide and dulaglutide) reduce BE frequency and comorbidities in addition to favorable psychiatric side effect profile compared to current options. However, large-scale, blinded placebo-controlled trials are lacking. Conclusion: Early findings suggest promising effects of GLP-1RAs on BEB. However, rigorous clinical trials are needed to firmly establish efficacy, dosing, safety, and comparative effectiveness before considering GLP-1RAs a viable novel approach.

Indexed as

BEDBinge Eating DisorderBulimia nervosaDulaglutideEating DisordersGlucagon-like peptide-1 receptor agonistLiraglutideSemaglutide

Identifiers

PMID38449772
PMCPMC10915596
OpenAlexW4392303338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.