Evidence map›Paper›PMID 38449700›Full record

ReviewNarra J2022

Acute severe hepatitis of unknown etiology in children: A mini-review.

Andri Frediansyah, Malik Sallam, Amanda Yufika, Khan Sharun, Muhammad Iqhrammullah, Deepak Chandran, Sukamto S Mamada, Dina E Sallam, Yousef Khader, Yohannes K Lemu and 18 more

Open access · diamondAbstract readReview
In one paragraph

Review in Narra J, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 20 countries.

Andri FrediansyahNational Research and Innovation Agency (BRIN), Yogyakarta, Indonesia.
Malik SallamDepartment of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman, Jordan.
Amanda YufikaDepartment of Family Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Khan SharunDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Muhammad IqhrammullahGraduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Deepak ChandranDepartment of Veterinary Sciences and Animal Husbandry, Amrita School of Agricultural Sciences, Amrita Vishwa Vidyapeetham University, Coimbatore, India.
Sukamto S MamadaDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia.
Dina E SallamPediatrics and Pediatric Nephrology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Yousef KhaderJordan University of Science and Technology, Irbid, Jordan.
Yohannes K LemuDepartment of Health, Behavior and Society, Jimma University, Jimma, Ethiopia.
Fauzi YusufGastroenterohepatology Division, Internal Medicine Department, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
James-Paul KretchyPublic Health Unit, School of Medicine and Health Sciences, Central University, Accra, Ghana.
Ziad AbdeenAl-Quds Nutrition and Health Research Institute, Faculty of Medicine, Al-Quds University, Abu Dies, Palestine.
J Smith Torres-RomanUniversidad Cientifica del Sur, Lima, Peru.
Yogesh AcharyaWestern Vascular Institute, University Hospital Galway, National University of Ireland Galway, Galway, Ireland.
Anastasia BondarenkoPediatric Infectious Disease and Pediatric Immunology Department, Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Aamer IkramNational Institutes of Health, Islamabad, Pakistan.
Kurnia F JamilDivision of Tropical Medicine & Infectious Disease, Department of Internal Medicine Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Katarzyna KotfisDepartment of Anesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, ICREA, CIBERSAM, ISCIII, Barcelona, Spain.
Lee SmithCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Dewi MegawatiDepartment of Veterinary Pathobiology, University of Missouri, Columbia, US.
Marius RademakerWaikato Clinical Campus, University of Auckland Medical School, Hamilton, New Zealand.
Talha B EmranDepartment of Pharmacy, BGC Trust University Bangladesh Chittagong, Bangladesh.
Ziad A MemishResearch & Innovation CentreKing Saud Medical City, Ministry of Health Riyadh, Saudi Arabia.
Sandro VentoFaculty of Medicine, University of Puthisastra, Phnom Penh, Cambodia.
Firzan NainuDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia.
Harapan HarapanMedical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Universitas Syiah Kuala · IDHasanuddin University · IDAin Shams University · EGAlfaisal University · SAAl-Quds University · PSAmrita Vishwa Vidyapeetham · INAnglia Ruskin University · GBBGC Trust University Bangladesh · BDCentral University · GHCentro de Investigación Biomédica en Red de Salud Mental · ESIndian Veterinary Research Institute · INJimma University · ETJordan University of Science and Technology · JONational Institute of Health · PKNational Research and Innovation Agency · IDOllscoil na Gaillimhe – University of Galway · IEPomeranian Medical University · PLShupyk National Healthcare University of Ukraine · UAUniversidad Científica del Sur · PEUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of acute, severe non hepA-E hepatitis of unknown etiology (ASHUE) has attracted global concern owing to the very young age of the patients and its unknown etiology. Although this condition has been linked to several possible causes, including viral infection, drugs and/or toxin exposure, the exact cause remains unknown; this makes treatment recommendation very difficult. In this review, we summarize recent updates on the clinical manifestations, complemented with laboratory results, case numbers with the global distribution and other epidemiological characteristics, and the possible etiologies. We also provide the proposed actions that could be undertaken to control and prevent further spread of this hepatitis. Since many etiological and pathological aspects of the acute non hepA-E hepatitis remain unclear, further research is needed to minimize the severe impact of this disease.

Indexed as

Acute non hepA–E hepatitisclinical manifestationsepidemiological characteristicsoutbreakprevention

Identifiers

PMID38449700
PMCPMC10914120
OpenAlexW4281675026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.