Evidence map›Paper›PMID 38449455›Full record

ArticleThe world journal of men's health2025

The Importance of Discordant Follicle Stimulating Hormone and Inhibin B Levels in Primary Infertile Men: Findings from a Cross-Sectional Study.

Fausto Negri, Luca Boeri, Simone Cilio, Edoardo Pozzi, Federico Belladelli, Christian Corsini, Massimiliano Raffo, Giuseppe Fallara, Eugenio Ventimiglia, Luigi Candela and 3 more

Open access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Fausto NegriVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-3677-6412
Luca BoeriDepartment of Urology, Foundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0003-0040-784X
Simone CilioVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-8431-9830
Edoardo PozziVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-0228-7039
Federico BelladelliVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-2165-659X
Christian CorsiniVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0001-9603-1589
Massimiliano RaffoDivision of Experimental Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID https://orcid.org/0000-0001-6644-6521
Giuseppe FallaraDivision of Experimental Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID https://orcid.org/0000-0001-7872-2650
Eugenio VentimigliaDivision of Experimental Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID https://orcid.org/0000-0003-3654-1629
Luigi CandelaVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-0593-8802
Alessia d'ArmaDivision of Experimental Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID https://orcid.org/0000-0002-4855-4577
Francesco MontorsiVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-7267-4181
Andrea SaloniaVita-Salute San Raffaele University, Milan, Italy.ORCID https://orcid.org/0000-0002-0595-7165
Vita-Salute San Raffaele University · ITIRCCS Ospedale San Raffaele · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

Fondazione Amici di URI Onlus, via URI-Urological Research Institute unrestricted grants
6 · The paper itself

Abstract

purposeWe aimed to investigate the relationship between follicle stimulating hormone (FSH) and inhibin B (InhB). MATERIALS AND

methodsData from 1,230 consecutive men presenting for primary couple's infertility were analyzed. Health-significant comorbidities were scored with Charlson comorbidity index. Quartiles of FSH and InhB were considered to determine threshold values. Descriptive statistics and logistic regression models tested association between FSH and InhB values.

resultsOverall, 1,080 (87.8%) men had concordant FSH and InhB values. Conversely, 150 patients (12.2%) had discrepancies in FSH and InhB, with 78 (6.3%) and 72 (5.9%) men reporting both low and high FSH and InhB values, respectively. Infertile men with discordant values were younger (median [interquartile range] 38.0 years [34-41 years]

conclusionsMore than one out of ten infertile men had discordant FSH and InhB values in the real-life setting showing worse clinical profiles than those with concordant levels. Smaller TV and history of cryptorchidism could be used as clinical markers to better tailor the need to test InhB.

Indexed as

Follicle stimulating hormoneInfertility, maleInhibin BReproductive healthSemen analysis

Identifiers

PMID38449455
PMCPMC11704173
OpenAlexW4392832965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.