Evidence map›Paper›PMID 38449391›Full record

ArticleActa biochimica et biophysica Sinica2024

The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells.

Qidi Huang, Shurong Zheng, Huayan Gu, Zhi Yang, Yiqiao Lu, Xia Yu, Guilong Guo

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Oncology letters · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Role of Ubiquitin-regulated EMT in Cancer Metastasis and Chemoresistance.International journal of biological sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qidi HuangDepartment of Breast Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Shurong ZhengDepartment of Breast Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Huayan GuDepartment of Breast Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Zhi YangDepartment of Breast Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Yiqiao LuDepartment of Breast Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Xia YuDepartment of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Guilong GuoDepartment of Breast Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
First Affiliated Hospital of Wenzhou Medical University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) has a high recurrence rate, metastasis rate and mortality rate. The aim of this study is to identify new targets for the treatment of TNBC. Clinical samples are used for screening deubiquitinating enzymes (DUBs). MDA-MB-231 cells and a TNBC mouse model are used for

Indexed as

Breast NeoplasmsDeubiquitinating EnzymesTriple Negative Breast NeoplasmsZinc Finger E-box-Binding Homeobox 1AnimalsCell Line, TumorCell MovementCell ProliferationEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansMiceBRCC3 protein, humanBRCC3 protein, mouseDeubiquitinating EnzymesZEB1 protein, humanZEB1 protein, mouseZinc Finger E-box-Binding Homeobox 1BRCC3epithelial-mesenchymal transitiontriple negative breast cancerZEB1

Identifiers

PMID38449391
PMCPMC11090844
OpenAlexW4391146729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.