Evidence map›Paper›PMID 38448963›Full record

ArticleBiomedical engineering online2024

Designing and validating an experimental protocol to induce airway narrowing in older adults with and without asthma.

Shaghayegh Chavoshian, Xiaoshu Cao, Anirudh Thommandram, Matthew B Stanbrook, Susan M Tarlo, Yan Fossat, Azadeh Yadollahi

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical engineering online, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Exploring the role of cold air in airway hyperresponsiveness and asthma diagnostic testing: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Shaghayegh ChavoshianKITE Research Institute, Toronto Rehabilitation Institute, University Health Network, 550 University Ave, Toronto, M5G 2A2, ON, Canada.
Xiaoshu CaoKITE Research Institute, Toronto Rehabilitation Institute, University Health Network, 550 University Ave, Toronto, M5G 2A2, ON, Canada.
Anirudh ThommandramLabs Department, Klick Health, Klick Inc, 175 Bloor St. East, Toronto, M4W 3R8, ON, Canada.
Matthew B StanbrookDepartment of Medicine, University of Toronto, 164 College St., Toronto, M5S 3G9, ON, Canada.
Susan M TarloDepartment of Medicine, University of Toronto, 164 College St., Toronto, M5S 3G9, ON, Canada.
Yan FossatLabs Department, Klick Health, Klick Inc, 175 Bloor St. East, Toronto, M4W 3R8, ON, Canada.
Azadeh YadollahiKITE Research Institute, Toronto Rehabilitation Institute, University Health Network, 550 University Ave, Toronto, M5G 2A2, ON, Canada. azadeh.yadollahi@uhn.ca.
Public Health Ontario · CAToronto Rehabilitation Institute · CAToronto Western Hospital · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersons with asthma may experience excessive airway narrowing due to exercise or exposure to cold air, worsening their daily functionality. Exercise has several benefits for asthma control, but it may induce airway narrowing in some persons with asthma. When combined with cold temperatures, it introduces another layer of challenges. Therefore, managing this interaction is crucial to increase the quality of life in individuals with asthma. The purpose of this study was to develop a reliable experimental protocol to assess the effects of exercise and cold air on airway narrowing in adults with asthma in a controlled and safe environment.

methodsThis study was a randomized cross-over study in adults with and without asthma. Participants underwent a protocol involving a 10-min seated rest, followed by a 10-min cycling on a stationary bike in different temperatures of 0, 10, or 20

resultsA total of 23 persons with asthma (11 females, age: 56.3 ± 10.9 years, BMI: 27.4 ± 5.7 kg/m

conclusionIn conclusion, our findings suggest that exposure to cold temperatures of 0

Indexed as

AsthmaQuality of LifeAgedCold TemperatureFemaleHumansMiddle AgedRandomized Controlled Trials as TopicRespirationTemperatureAirway narrowingAsthmaCold temperatureExerciseExperimental protocol

Identifiers

PMID38448963
PMCPMC10916193
OpenAlexW4392511579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.