Evidence map›Paper›PMID 38448895›Full record

Trial reportBMC psychiatry2024

Prediction of the efficacy of group cognitive behavioral therapy using heart rate variability based smart wearable devices: a randomized controlled study.

Zexin Lin, Junjie Zheng, Yang Wang, Zhao Su, Rongxin Zhu, Rongxun Liu, Yange Wei, Xizhe Zhang, Fei Wang

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05913349 (Effectiveness of Group Cognitive Behavioral Therapy for Psychological Sub-health), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05913349 naunknown statusnot on this map

Effectiveness of Group Cognitive Behavioral Therapy for Psychological Sub-health: A Randomized Controlled Trial

TypeinterventionalSponsorJiangsu Province Nanjing Brain HospitalRan2021 to 2024Enrolled60ConditionsMental SufferingArmsGroup Cognitive Behavioral Therapy (GCBT)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zexin Lin *Early Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China.
Junjie Zheng *Early Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China.
Yang Wang *Early Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China.
Zhao SuSchool of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, Jiangsu, China.
Rongxin ZhuEarly Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China.
Rongxun LiuEarly Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China.
Yange WeiEarly Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China.
Xizhe ZhangSchool of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, Jiangsu, China. zhangxizhe@njmu.edu.cn.
Fei WangEarly Intervention Unit, Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, P.R. China. fei.wang@yale.edu.

Funding

Henan Province Higher Education Teaching Reform Research and Practice Project 2021SJGLX189Jiangsu Provincial Key Research and Development Program BE2021617Jiangsu Provincial Key Research and Development Program BE2022160Medical Science and Technology Development Foundation of Jiangsu Commission of Health ZD2021026National Natural Science Foundation of China 62176129National Natural Science Foundation of China 82151315NSFC-Guangdong Joint Fund U20A6005
6 · The paper itself

Abstract

backgroundDepression and anxiety are common and disabling mental health problems in children and young adults. Group cognitive behavioral therapy (GCBT) is considered that an efficient and effective treatment for these significant public health concerns, but not all participants respond equally well. The aim of this study was to examine the predictive ability of heart rate variability (HRV), based on sensor data from consumer-grade wearable devices to detect GCBT effectiveness in early intervention.

methodsIn a study of 33 college students with depression and anxiety, participants were randomly assigned to either GCBT group or a wait-list control (WLC) group. They wore smart wearable devices to measure their physiological activities and signals in daily life. The HRV parameters were calculated and compared between the groups. The study also assessed correlations between participants' symptoms, HRV, and GCBT outcomes.

resultsThe study showed that participants in GCBT had significant improvement in depression and anxiety symptoms after four weeks. Higher HRV was associated with greater improvement in depressive and anxious symptoms following GCBT. Additionally, HRV played a noteworthy role in determining how effective GCBT was in improve anxiety(P = 0.002) and depression(P = 0.020), and its predictive power remained significant even when considering other factors.

conclusionHRV may be a useful predictor of GCBT treatment efficacy. Identifying predictors of treatment response can help personalize treatment and improve outcomes for individuals with depression and anxiety.

trial registrationThe trial has been retrospectively registered on [22/06/2023] with the registration number [NCT05913349] in the ClinicalTrials.gov. Variations in heart rate variability (HRV) have been associated with depression and anxiety, but the relationship of baseline HRV to treatment outcome in depression and anxiety is unclear. This study predicted GCBT effectiveness using HRV measured by wearable devices. 33 students with depression and anxiety participated in a trial comparing GCBT and wait-list control. HRV parameters from wearables correlated with symptoms (PHQ, PSS) and GCBT effectiveness. Baseline HRV levels are strongly associated with GCBT treatment outcomes. HRV may serve as a useful predictor of efficacy of GCBT treatment,facilitating personalized treatment approaches for individuals with depression and anxiety.

Indexed as

Cognitive Behavioral TherapyWearable Electronic DevicesAnxietyChildHeart RateHumansResearch DesignYoung AdultAnxietyDepressionGroup cognitive behavioral therapyHeart rate variabilityPrediction

Identifiers

PMID38448895
PMCPMC10916138

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.