Evidence map›Paper›PMID 38448847›Full record

SynthesisBMC infectious diseases2024

A dengue virus infection in Ethiopia: a systematic review and meta-analysis.

Eshetu Nigussie, Daniel Atlaw, Getahun Negash, Habtamu Gezahegn, Girma Baressa, Alelign Tasew, Demisu Zembaba

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eshetu NigussieDepartment of Medical Laboratory Science, School of Medicine, Madda Walabu University, Addis Ababa, Ethiopia. eshetunba@gmail.com.
Daniel AtlawDepartment of Biomedical Science, School of Medicine, Madda Walabu University, Addis Ababa, Ethiopia.
Getahun NegashDepartment of Medical Laboratory Science, School of Medicine, Madda Walabu University, Addis Ababa, Ethiopia.
Habtamu GezahegnDepartment of Biomedical Science, School of Medicine, Madda Walabu University, Addis Ababa, Ethiopia.
Girma BaressaDepartment of Public Health, School of Health Science, Madda Walabu University, Addis Ababa, Ethiopia.
Alelign TasewDepartment of Public Health, School of Health Science, Madda Walabu University, Addis Ababa, Ethiopia.
Demisu ZembabaDepartment of Public Health, School of Health Science, Madda Walabu University, Addis Ababa, Ethiopia.
Madda Walabu University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDengue is caused by a positive-stranded RNA virus called dengue virus, which is spread by Aedes mosquito species. It is a fast-growing acute febrile disease with potentially lethal consequences that is a global public health problem, mostly in tropical and subtropical countries. In Ethiopia, dengue fever is understudied, although the virus is still being transmitted and viral infection rates are rising. This systematic review and meta-analysis was aimed at estimating the pooled prevalence of DENV infection in Ethiopia.

methodsA literature search was done on the PubMed, Hinari and Google Scholar databases to identify studies published before July, 2023. Random effects and fixed effects models were used to estimate the pooled prevalence of all three markers. The Inconsistency Index was used to assess the level of heterogeneity.

resultsA total of 11 studies conducted on suspected individuals with dengue fever and acutely febrile participants were included in this review. The majority of the studies had a moderate risk of bias and no study had a high risk of bias. A meta-analysis estimated a pooled IgG prevalence of 21% (95% CI: 19-23), a pooled IgM prevalence of 9% (95%CI: 4-13) and a pooled DENV-RNA prevalence of 48% (95% CI: 33-62). There is evidence of possible publication bias in IgG but not in the rest of the markers.

conclusionDengue is prevalent among the dengue fever suspected and febrile population in Ethiopia. Healthcare providers, researchers and policymakers should give more attention to dengue fever.

Indexed as

AedesDengueAnimalsDatabases, FactualEthiopiaFeverHumansImmunoglobulin GImmunoglobulin GDengueDengue virusEthiopiaMeta-analysisSystematic review

Identifiers

PMID38448847
PMCPMC10918862
OpenAlexW4392499103

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.