Evidence map›Paper›PMID 38448737›Full record

ArticleCellular and molecular life sciences : CMLS2024

Tektin bundle interacting protein, TEKTIP1, functions to stabilize the tektin bundle and axoneme in mouse sperm flagella.

Xin-Yan Geng, Hui-Juan Jin, Lan Xia, Bin-Bin Wang, Su-Ren Chen

Open access · goldAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xin-Yan GengKey Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, 100875, People's Republic of China.
Hui-Juan JinKey Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, 100875, People's Republic of China.
Lan XiaKey Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, 100875, People's Republic of China.
Bin-Bin WangCenter for Genetics, National Research Institute of Family Planning, Beijing, 100081, China. wbbahu@163.com.
Su-Ren ChenKey Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, Department of Biology, College of Life Sciences, Beijing Normal University, Beijing, 100875, People's Republic of China. chensr@bnu.edu.cn.ORCID http://orcid.org/0000-0002-9337-5412
Beijing Normal University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

National Key Research and Development Project 2019YFA0802101National Natural Science Foundation of China 32370905
6 · The paper itself

Abstract

Tektins are microtubule inner proteins (MIPs) and localize at the inside lumen of doublet microtubules (DMTs) of cilia/flagella. TEKTIP1, a newly identified protein by cryo-electron microscopy (cryo-EM), is proposed to be localized at the center of the tektin bundle and hypothesized to recruit tektins or stabilize the bundle. However, the physiological role of TEKTIP1 is unknown. In this study, we generated Tektip1-knockout (Tektip1

Indexed as

AxonemeMicrotubule ProteinsSemenAnimalsCryoelectron MicroscopyFemaleFlagellaHumansMaleMiceSpermatozoaSperm MotilityMicrotubule ProteinstektinsKnockout miceMicrotubule inner proteinSperm motilityTektinsTEKTIP1

Identifiers

PMID38448737
PMCPMC10917850
OpenAlexW4392759168

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.