Evidence map›Paper›PMID 38448649›Full record

ReviewAAPS PharmSciTech2024

Recent Trends in Nanocarrier-Based Drug Delivery System for Prostate Cancer.

Amit Kumar, Akshay Kumar Lunawat, Ashutosh Kumar, Tarun Sharma, Md Moidul Islam, Milan Singh Kahlon, Debanjan Mukherjee, Raj Kumar Narang, Sarjana Raikwar

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Amit KumarDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Akshay Kumar LunawatDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Ashutosh KumarDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Tarun SharmaDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Md Moidul IslamDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Milan Singh KahlonDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Debanjan MukherjeeDepartment of Quality Assurance, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Raj Kumar NarangDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Sarjana RaikwarDepartment of Pharmaceutics, ISF College of Pharmacy, Moga, 142001, Punjab, India. sarjanaraikwar@gmail.com.ORCID http://orcid.org/0000-0002-1476-9684
Indo Soviet Friendship College of Pharmacy · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer remains a significant global health concern, requiring innovative approaches for improved therapeutic outcomes. In recent years, nanoparticle-based drug delivery systems have emerged as promising strategies to address the limitations of conventional cancer chemotherapy. The key trends include utilizing nanoparticles for enhancing drug delivery to prostate cancer cells. Nanoparticles have some advantages such as improved drug solubility, prolonged circulation time, and targeted delivery of drugs. Encapsulation of chemotherapeutic agents within nanoparticles allows for controlled release kinetics, reducing systemic toxicity while maintaining therapeutic efficacy. Additionally, site-specific accumulation within the prostate tumor microenvironment is made possible by the functionalization of nanocarrier with targeted ligands, improving therapeutic effectiveness. This article highlights the basics of prostate cancer, statistics of prostate cancer, mechanism of multidrug resistance, targeting approach, and different types of nanocarrier used for the treatment of prostate cancer. It also includes the applications of nanocarriers for the treatment of prostate cancer and clinical trial studies to validate the safety and efficacy of the innovative drug delivery systems. The article focused on developing nanocarrier-based drug delivery systems, with the goal of translating these advancements into clinical applications in the future.

Indexed as

NanoparticlesProstatic NeoplasmsDrug Delivery SystemsHumansKineticsMaleSolubilityTumor Microenvironmentclinical trialsmultidrug resistancenanocarriersprostate cancertargeting approach

Identifiers

PMID38448649
OpenAlexW4392501746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.