Evidence map›Paper›PMID 38448588›Full record

ArticleNature2024

A vagal reflex evoked by airway closure.

Michael S Schappe, Philip A Brinn, Narendra R Joshi, Rachel S Greenberg, Soohong Min, AbdulRasheed A Alabi, Chuchu Zhang, Stephen D Liberles

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. VipCell reports · 2026
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  4. Piezo channels in tumors.Journal of cancer research and clinical oncology · 2026
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  8. Rewiring the Lung-CNS Axis After Spinal Cord Injury.Journal of inflammation research · 2026
    Review
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  13. Molecular, anatomical, and functional organization of lung interoceptors.bioRxiv : the preprint server for biology · 2025
    Article
  14. Review
  15. Article
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  17. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michael S SchappeDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Philip A BrinnDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.ORCID 0009-0007-2262-1851
Narendra R JoshiDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5030-389X
Rachel S GreenbergDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Soohong MinDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
AbdulRasheed A AlabiDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Chuchu ZhangDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
Stephen D LiberlesDepartment of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA. Stephen_Liberles@hms.harvard.edu.ORCID 0000-0002-2177-9741
Howard Hughes Medical Institute · US

Funding

Sensory receptors of the vagus nerveDP1AT009497 · NCCIH · HARVARD MEDICAL SCHOOL · PI LIBERLES, STEPHEN DANIEL · 2016 to 2020
$5.9M
Sensory biology of respiratory control neurons in the vagus nerveR01HL132255 · NHLBI · HARVARD MEDICAL SCHOOL · PI LIBERLES, STEPHEN DANIEL · 2016 to 2019
$1.7M
Neural-Epithelial Encoding of Airway SensesF32HL156583 · NHLBI · HARVARD MEDICAL SCHOOL · PI SCHAPPE, MICHAEL STEPHEN · 2021 to 2023
$205k
NCCIH NIH HHS DP1 AT009497NHLBI NIH HHS F32 HL156583NHLBI NIH HHS R01 HL132255
6 · The paper itself

Abstract

Airway integrity must be continuously maintained throughout life. Sensory neurons guard against airway obstruction and, on a moment-by-moment basis, enact vital reflexes to maintain respiratory function

Indexed as

LungReflexRespirationRespiratory MechanicsVagus NerveAnimalsEpithelial CellsFemaleIon ChannelsLung ComplianceMaleMechanoreceptorsMiceParvalbuminsSensory Receptor CellsIon ChannelsParvalbuminsPiezo2 protein, mouse

Identifiers

PMID38448588
PMCPMC10972749
OpenAlexW4392505465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.