Evidence map›Paper›PMID 38448585›Full record

ArticleNature2024

Decoding chromatin states by proteomic profiling of nucleosome readers.

Saulius Lukauskas, Andrey Tvardovskiy, Nhuong V Nguyen, Mara Stadler, Peter Faull, Tina Ravnsborg, Bihter Özdemir Aygenli, Scarlett Dornauer, Helen Flynn, Rik G H Lindeboom and 10 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. SMARCD1 and Its Functional Relevance in SWI/SNF and Cancer.International journal of molecular sciences · 2026
    Review
  7. Review
  8. piRNA direct the chromatin reader to its genomic targets.bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 6 countries.

Saulius Lukauskas *Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
Andrey Tvardovskiy *Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
Nhuong V Nguyen *MRC Laboratory of Medical Sciences (LMS), London, UK.ORCID 0000-0003-4152-5113
Mara StadlerInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
Peter FaullMRC Laboratory of Medical Sciences (LMS), London, UK.ORCID 0000-0001-8491-8086
Tina RavnsborgVILLUM Center for Bioanalytical Sciences and Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID 0000-0002-6376-621X
Bihter Özdemir AygenliInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-0234-7169
Scarlett DornauerInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
Helen FlynnProteomic Sciences Technology Platform, The Francis Crick Institute, London, UK.ORCID 0000-0001-7002-9130
Rik G H LindeboomDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.ORCID 0000-0002-3660-504X
Teresa K BarthMetabolomics and Proteomics Core, Helmholtz Zentrum München, Munich, Germany.
Kevin BrockersInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-6485-5935
Stefanie M HauckMetabolomics and Proteomics Core, Helmholtz Zentrum München, Munich, Germany.ORCID 0000-0002-1630-6827
Michiel VermeulenDepartment of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands.
Ambrosius P SnijdersProteomic Sciences Technology Platform, The Francis Crick Institute, London, UK.
Christian L MüllerInstitute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Peter A DiMaggioDepartment of Chemical Engineering, Imperial College London, London, UK.
Ole N JensenVILLUM Center for Bioanalytical Sciences and Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.ORCID 0000-0003-1862-8528
Robert SchneiderInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
Till BartkeInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany. till.bartke@helmholtz-munich.de.ORCID 0000-0002-6584-2140
Helmholtz Zentrum München · DERadboud University Nijmegen · NLThe Francis Crick Institute · GBUniversity of Southern Denmark · DKCenter for Integrated Protein Science Munich · DEHelmholtz Association of German Research Centres · DEImperial College London · GBMRC London Institute of Medical Sciences · GBNorthwestern University · US

Funding

Medical Research Council MC_UP_1102/2Wellcome Trust FC001999
6 · The paper itself

Abstract

DNA and histone modifications combine into characteristic patterns that demarcate functional regions of the genome

Indexed as

ChromatinChromatin Assembly and DisassemblyNuclear ProteinsNucleosomesProteomicsBinding SitesDNAEnhancer Elements, GeneticHeterochromatinHistonesHumansPromoter Regions, GeneticProtein BindingChromatinDNAHeterochromatinHistonesNuclear ProteinsNucleosomes

Identifiers

PMID38448585
PMCPMC10954555
OpenAlexW4392504741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.