Evidence map›Paper›PMID 38448562›Full record

ReviewNature reviews. Genetics2024

Genetics of chronic respiratory disease.

Ian Sayers, Catherine John, Jing Chen, Ian P Hall

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  9. Review
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  13. Genome-wide Association Study IdentifiesAllergy, asthma & immunology research · 2026
    Article
  14. Article
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  16. Article
  17. Genomic Locus Tagged by Lung Function GWAS SNV rs12477314 (2q37.3) Acts as a Regulatory Region for a Systemic Inflammatory Phenotype.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ian SayersNIHR Nottingham Biomedical Research Centre, University of Nottingham, University Park, Nottingham, UK.
Catherine JohnUniversity of Leicester, Leicester, UK.
Jing ChenUniversity of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0003-1287-1930
Ian P HallNIHR Nottingham Biomedical Research Centre, University of Nottingham, University Park, Nottingham, UK. ian.hall@nottingham.ac.uk.ORCID http://orcid.org/0000-0001-9933-3216
University of Leicester · GBUniversity of Nottingham · GB

Funding

Wellcome Trust 225221
6 · The paper itself

Abstract

Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD), asthma and interstitial lung diseases are frequently occurring disorders with a polygenic basis that account for a large global burden of morbidity and mortality. Recent large-scale genetic epidemiology studies have identified associations between genetic variation and individual respiratory diseases and linked specific genetic variants to quantitative traits related to lung function. These associations have improved our understanding of the genetic basis and mechanisms underlying common lung diseases. Moreover, examining the overlap between genetic associations of different respiratory conditions, along with evidence for gene-environment interactions, has yielded additional biological insights into affected molecular pathways. This genetic information could inform the assessment of respiratory disease risk and contribute to stratified treatment approaches.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveChronic DiseaseGene-Environment InteractionGenetic Predisposition to DiseaseGenetic VariationGenome-Wide Association StudyHumansLung Diseases, InterstitialMultifactorial Inheritance

Identifiers

PMID38448562
PMCPMC7618436
OpenAlexW4392503842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.