Evidence map›Paper›PMID 38448541›Full record

ArticleScientific reports2024

Effect of very long-term storage and multiple freeze and thaw cycles on 11-dehydro-thromboxane-B

Giovanna Petrucci, Duaa Hatem, Ruth Langley, Siobhan Cleary, Aleksandra Gentry-Maharaj, Dario Pitocco, Alessandro Rizzi, Paola Ranalli, Francesco Zaccardi, Aida Habib and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Cortisol Stability at 16 and 30 Years in Urine Specimens Stored at -20°C.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
  2. Oxidative stress and fetal weight: observational findings from a pregnancy cohort in New York City.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Giovanna PetrucciDepartment of Bioethics and Safety, Section of Pharmacology, Catholic University School of Medicine, Rome, Italy. giovanna.petrucci@unicatt.it.
Duaa HatemDepartment of Bioethics and Safety, Section of Pharmacology, Catholic University School of Medicine, Rome, Italy.
Ruth LangleyMedical Research Council (MRC) Clinical Trials Units at University College London (UCL), London, UK.
Siobhan ClearyMedical Research Council (MRC) Clinical Trials Units at University College London (UCL), London, UK.
Aleksandra Gentry-MaharajMedical Research Council (MRC) Clinical Trials Units at University College London (UCL), London, UK.
Dario PitoccoDiabetology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Alessandro RizziDiabetology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Paola RanalliDepartment of Hematology, S. Spirito Hospital, Pescara, Italy.
Francesco ZaccardiLeicester Real World Evidence Unit, Leicester Diabetes Centre, University of Leicester, Leicester, UK.
Aida HabibDepartment of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar.
Bianca RoccaDepartment of Bioethics and Safety, Section of Pharmacology, Catholic University School of Medicine, Rome, Italy.
Agostino Gemelli University Polyclinic · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITMedical Research Council · GBMRC Clinical Trials Unit at UCL · GBOspedale di Santo Spirito · ITQatar University · QAUniversity College London · GBUniversity of Leicester · GB

Funding

AsCaP collaboration C569/A24991#2Cancer Research UK 15015Cancer Research UK 19252catholic university school of medicine, Rome, Italy Linea D1 2021 and Linea D1 2022
6 · The paper itself

Abstract

Biological samples are often frozen and stored for years and/or thawed multiple times, thus assessing their stability on long-term storage and repeated freeze-thaw cycles is crucial. The study aims were to assess:-the long-term stability of two major enzymatic and non-enzymatic metabolites of arachidonic acid, i.e. urinary 11-dehydro-thromboxane-(Tx) B

Indexed as

AntioxidantsProstaglandins FArachidonic AcidCreatinineFreezingHumansImmunoenzyme TechniquesThromboxanesAntioxidantsArachidonic AcidCreatinineProstaglandins FThromboxanes

Identifiers

PMID38448541
PMCPMC10917770
OpenAlexW4392506581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.