Evidence map›Paper›PMID 38448409›Full record

ArticleNature communications2024

Deep learning model for personalized prediction of positive MRSA culture using time-series electronic health records.

Masayuki Nigo, Laila Rasmy, Bingyu Mao, Bijun Sai Kannadath, Ziqian Xie, Degui Zhi

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Staphylococcus aureus-vascular endothelium interactions: Mechanisms and therapeutic opportunities.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
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  18. Risk Factors for Methicillin-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masayuki NigoMcGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA. mnigo@houstonmethodist.org.ORCID 0000-0003-4898-1808
Laila RasmyMcWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-2644-4908
Bingyu MaoMcWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0009-0000-5428-8079
Bijun Sai KannadathDepartment of Internal Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA.ORCID 0000-0002-0177-6834
Ziqian XieMcWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, USA.
Degui ZhiMcWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0001-7754-1890

Funding

Deep Learning Based Pharmacokinetic Model for VancomycinR01AI175699 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI NIGO, MASAYUKI · 2023 to 2025
$2.4M
NIAID NIH HHS R01 AI175699
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) poses significant morbidity and mortality in hospitals. Rapid, accurate risk stratification of MRSA is crucial for optimizing antibiotic therapy. Our study introduced a deep learning model, PyTorch_EHR, which leverages electronic health record (EHR) time-series data, including wide-variety patient specific data, to predict MRSA culture positivity within two weeks. 8,164 MRSA and 22,393 non-MRSA patient events from Memorial Hermann Hospital System, Houston, Texas are used for model development. PyTorch_EHR outperforms logistic regression (LR) and light gradient boost machine (LGBM) models in accuracy (AUROC

Indexed as

Deep LearningMethicillin-Resistant Staphylococcus aureusCritical CareElectronic Health RecordsHospitalsHumans

Identifiers

PMID38448409
PMCPMC10917736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.