Evidence map›Paper›PMID 38448165›Full record

ArticleAJNR. American journal of neuroradiology2024

Compatibility of Standard Vagus Nerve Stimulation and Investigational Microburst Vagus Nerve Stimulation Therapy with fMRI.

Erik H Middlebrooks, Jerzy P Szaflarski, Jason Begnaud, Ashesh Thaker, Kenny Henderson, Mark Bolding, Jill A Sellers, Jane Allendorfer

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Erik H MiddlebrooksFrom the Department of Neuroradiology (E.H.M.), Mayo Clinic College of Medicine and Science, Jacksonville, Florida Middlebrooks.erik@mayo.edu.
Jerzy P SzaflarskiDepartment of Neurology (J.P.S., M.B., J.A.), Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Jason BegnaudNeuromodulation Division (J.B., K.H.), LivaNova USA, Houston, Texas.
Ashesh ThakerDepartmentd of Neuroradiology (A.T.) and Radiology, Denver Health, University of Colorado School of Medicine, Denver, Colorado.ORCID 0000-0001-5238-0429
Kenny HendersonNeuromodulation Division (J.B., K.H.), LivaNova USA, Houston, Texas.
Mark BoldingDepartment of Neurology (J.P.S., M.B., J.A.), Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-7684-4125
Jill A SellersSellers Communications LLC (J.A.S.), Springfield, Missouri.ORCID 0000-0002-5241-9159
Jane AllendorferDepartment of Neurology (J.P.S., M.B., J.A.), Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-6888-9000
University of Alabama at Birmingham · USLivaNova (United States) · USJacksonville College · USMissouri State University · USUniversity of Colorado Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vagus nerve stimulation devices are conditionally approved for MR imaging with stimulation turned off, and the requirement to modify the stimulation settings may be a barrier to scanning in some radiology practices. There is increasing interest in studying the effects of stimulation during MR imaging/fMRI. This study evaluated the safety of standard and investigational microburst vagus nerve stimulation therapies during MR imaging/fMRI. A prospective, multicenter study was conducted in patients with an investigational vagus nerve stimulation device that delivered either standard or investigational microburst vagus nerve stimulation. Thirty participants underwent sequential MR imaging and fMRI scans, encompassing 188 total hours of scan time (62.7 hours with standard vagus nerve stimulation and 125.3 hours with investigational microburst vagus nerve stimulation). No adverse events were reported with active stimulation during MR imaging or during 12 months of follow-up. Our results support the safety of standard and investigational microburst vagus nerve stimulation therapy during MR imaging and fMRI scans.

Indexed as

Magnetic Resonance ImagingVagus Nerve StimulationAdultAgedBrainFemaleHumansMaleMiddle AgedProspective StudiesTreatment Outcome

Identifiers

PMID38448165
PMCPMC11383398
OpenAlexW4392519378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.