Evidence map›Paper›PMID 38447765›Full record

ArticleToxicon : official journal of the International Society on Toxinology2024

β-keto amyrin isolated from Cryptostegia grandiflora R. br. inhibits inflammation caused by Daboia russellii viper venom: Direct binding of β-keto amyrin to phospholipase A

K H Santhosh, V Krishna, K Kemparaju, H Manjunatha, R Shashi Kumar, A Mukherjee, S E Gomez Mejiba, D C Ramirez, B S Ravindranath

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicon : official journal of the International Society on Toxinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

K H SanthoshDepartment of Biotechnology and Bioinformatics, Kuvempu University, Jnana Sahyadri, Shankaraghatta-577451, Karnataka, India.
V KrishnaDepartment of Biotechnology and Bioinformatics, Kuvempu University, Jnana Sahyadri, Shankaraghatta-577451, Karnataka, India.
K KemparajuDepartment of Biochemistry, University of Mysore, Manasa Gangotri Campus, Mysore-57006, Karnataka, India.
H ManjunathaDepartment of Biochemistry, Jnana Bharathi Campus, Bangalore University, Bangalore- 56005, Karnataka, India.
R Shashi KumarDepartment of Biotechnology and Bioinformatics, Kuvempu University, Jnana Sahyadri, Shankaraghatta-577451, Karnataka, India.
A MukherjeeDepartment of Biotechnology, Manipal Institute of Technology, Manipal, Manipal Academy of Higher Education, Manipal- 576104, Karnataka, India.
S E Gomez MejibaLaboratory of Nutrition and Experimental Therapeutics, CCT-San Luis-National University of San Luis, San Luis, 5700-San Luis, Argentina. Electronic address: sandraegomezmejiba@yahoo.com.
D C RamirezLaboratory of Experimental and Translational Medicine. CCT-San Luis-National University of San Luis, San Luis, 5700-San Luis, Argentina. Electronic address: ramirezlabimibiosl@ymail.com.
B S RavindranathDepartment of Biotechnology, Manipal Institute of Technology, Manipal, Manipal Academy of Higher Education, Manipal- 576104, Karnataka, India. Electronic address: ravindranath.bs@manipal.edu.
Kuvempu University · INCentro Científico Tecnológico - San Luis · ARManipal Academy of Higher Education · INBangalore University · INUniversity of Mysore · IN

Funding

Free Radicals and Redox Signaling Triggered by Lipopolysccharide in MacrophagesR00ES015415 · NIEHS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI RAMIREZ, DARIO C · 2008 to 2010
$732k
NIEHS NIH HHS R00 ES015415
6 · The paper itself

Abstract

The search for mechanism-based anti-inflammatory therapies is of fundamental importance to avoid undesired off-target effects. Phospholipase A

Indexed as

ApocynaceaeDaboiaInflammationOleanolic AcidViper VenomsAnimalsAnti-Inflammatory AgentsDiclofenacMiceMolecular Docking SimulationPhospholipases A2Anti-Inflammatory Agentsbeta-amyrinDiclofenacOleanolic AcidPhospholipases A2Viper VenomsC. grandiflora extractDaboia russellii viper venomDockingInflammationMolecular dynamicsβ-keto amyrin-PLA(2) complex

Identifiers

PMID38447765
PMCPMC11194115
OpenAlexW4392821703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.