Evidence map›Paper›PMID 38447621›Full record

Trial reportJournal of pain and symptom management2024

Dyadic Yoga for Head and Neck Cancer Patients Undergoing Chemoradiation and their Family Caregivers.

Kathrin Milbury, David I Rosenthal, Yisheng Li, An Thuy Ngo-Huang, Smitha Mallaiah, Sania Yousuf, Clifton D Fuller, Carol Lewis, Eduardo Bruera, Lorenzo Cohen

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pain and symptom management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kathrin MilburyDepartment of Behavioral Science (K.M., S.Y.), 1155 Pressler St., Houston, Texas 77030, USA. Electronic address: kmilbury@mdanderson.org.
David I RosenthalDepartment of Radiation Oncology (D.I.R., C.D.F.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
Yisheng LiDepartment of Biostatistics (Y.L.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
An Thuy Ngo-HuangDepartment of Palliative, Rehabilitation & Integrative Medicine (A.T.N.-H., S.M., E.B.,L.C.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
Smitha MallaiahDepartment of Palliative, Rehabilitation & Integrative Medicine (A.T.N.-H., S.M., E.B.,L.C.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
Sania YousufDepartment of Behavioral Science (K.M., S.Y.), 1155 Pressler St., Houston, Texas 77030, USA.
Clifton D FullerDepartment of Radiation Oncology (D.I.R., C.D.F.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
Carol LewisDepartment of Head and Neck Surgery (C.L.), The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, Texas 77030, USA.
Eduardo BrueraDepartment of Palliative, Rehabilitation & Integrative Medicine (A.T.N.-H., S.M., E.B.,L.C.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
Lorenzo CohenDepartment of Palliative, Rehabilitation & Integrative Medicine (A.T.N.-H., S.M., E.B.,L.C.), 1515 Holcombe Blvd., Houston, Texas 77030, USA.
The University of Texas MD Anderson Cancer Center · USBehavioral Tech · US

Funding

Improving Health Utilization and Quality of Life in Head and Neck Cancer Patients Undergoing Chemoradiation and their Family CaregiversR01CA247307 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2020 to 2025
$2.3M
Couple-Based Mind-Body Program for Lung Cancer Patients and their PartnersK01AT007559 · NCCIH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2013 to 2017
$652k
NCCIH NIH HHS K01 AT007559NCI NIH HHS R01 CA247307
6 · The paper itself

Abstract

objectivesConcurrent chemoradiation to treat head and neck cancer (HNC) may result in debilitating toxicities. Targeted exercise such as yoga therapy may buffer against treatment-related sequelae; thus, this pilot RCT examined the feasibility and preliminary efficacy of a yoga intervention. Because family caregivers report low caregiving efficacy and elevated levels of distress, we included them in this trial as active study participants.

methodsHNC patients and their caregivers were randomized to a 15-session dyadic yoga program or a waitlist control (WLC) group. Prior to randomization, patients completed standard symptom (MDASI-HN) and patients and caregivers completed quality of life (SF-36) assessments. The 15-session program was delivered parallel to patients' treatment schedules. Participants were re-assessed at patients' last day of chemoradiation and again 30 days later. Patients' emergency department visits, unplanned hospital admissions and gastric feeding tube placements were recorded over the treatment course and up to 30 days later.

resultsWith a consent rate of 76%, 37 dyads were randomized. Participants in the yoga group completed a mean of 12.5 sessions and rated the program as "beneficial." Patients in the yoga group had clinically significantly less symptom interference and HNC symptom severity and better QOL than those in the WLC group. They were also less likely to have a hospital admission (OR = 3.00), emergency department visit (OR = 2.14), and/or a feeding tube placement (OR = 1.78).

conclusionYoga therapy appears to be a feasible, acceptable, and possibly efficacious behavioral supportive care strategy for HNC patients undergoing chemoradiation. A larger efficacy trial is warranted.

Indexed as

CaregiversChemoradiotherapyHead and Neck NeoplasmsQuality of LifeYogaAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsTreatment OutcomeChemoradiationHead and neck cancerYoga, Dyadic intervention, Symptoms, Quality of life, Family caregivers, Healthcare utilization, Gastric feeding tube, Hospital admission

Identifiers

PMID38447621
PMCPMC11349719
OpenAlexW4392470489

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.