Evidence map›Paper›PMID 38447101›Full record

ArticleACS sensors2024

Pyrene-Appended Boronic Acids on Graphene Foam Electrodes Provide Quantum Capacitance-Based Molecular Sensors for Lactate.

Simon M Wikeley, Jakub Przybylowski, Jordan E Gardiner, Tony D James, Philip J Fletcher, Mark A Isaacs, Pablo Lozano-Sanchez, Marco Caffio, Frank Marken

Open access · hybridAbstract read
In one paragraph

Article in ACS sensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Simon M WikeleyDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.
Jakub PrzybylowskiDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.
Jordan E GardinerDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.
Tony D JamesDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.
Philip J FletcherImaging Facility, University of Bath, Bath BA2 7AY, U.K.
Mark A IsaacsHarwellXPS, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, Harwell Campus, Didcot OX11 0FA, U.K.ORCID 0000-0002-0335-4272
Pablo Lozano-SanchezIntegrated Graphene Ltd., Euro House, Wellgreen Place, Stirling FK8 2DJ, U.K.
Marco CaffioIntegrated Graphene Ltd., Euro House, Wellgreen Place, Stirling FK8 2DJ, U.K.
Frank MarkenDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.ORCID 0000-0003-3177-4562
University of Bath · GBWalgreens (United States) · USResearch Complex at Harwell · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular recognition and sensing can be coupled to interfacial capacitance changes on graphene foam surfaces linked to double layer effects and coupled to enhanced quantum capacitance. 3D graphene foam film electrodes (Gii-Sens; thickness approximately 40 μm; roughness factor approximately 100) immersed in aqueous buffer media exhibit an order of magnitude jump in electrochemical capacitance upon adsorption of a charged molecular receptor based on pyrene-appended boronic acids (here, 4-borono-1-(pyren-2-ylmethyl)pyridin-1-ium bromide, or abbreviated T1). This pyrene-appended pyridinium boronic acid receptor is employed here as a molecular receptor for lactate. In the presence of lactate and at pH 4.0 (after pH optimization), the electrochemical capacitance (determined by impedance spectroscopy) doubles again. Lactic acid binding is expressed with a Hillian binding constant (

Indexed as

GraphiteLactic AcidBoronic AcidsElectrodesHumansSweatBoronic AcidsGraphiteLactic Acidgraphene foamlactate sensormolecular capacitancequantum capacitancewearable sensor

Identifiers

PMID38447101
PMCPMC10964244
OpenAlexW4392501341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.