Evidence map›Paper›PMID 38446992›Full record

Trial reportJournal of the International Association of Providers of AIDS Care

The Effect of a Group-Based Mindfulness and Acceptance Training on Psychological Flexibility and Adherence to Antiretroviral Therapy Among Adolescents in Uganda: An Open-Label Randomized Trial.

Khamisi Musanje, Moses R Kamya, Rosco Kasujja, Wouter Vanderplasschen, Deborah L Sinclair, Martin M Baluku, Raymond F Odokonyero, Charles P Namisi, John Mukisa, Ross G White and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Khamisi MusanjeClinical Epidemiology Unit, Makerere University, Kampala, Uganda.ORCID 0000-0003-2825-9105
Moses R KamyaDepartment of Medicine, Makerere University, Kampala, Uganda.
Rosco KasujjaDepartment of Mental Health and Community Psychology, Makerere University, Kampala, Uganda.
Wouter VanderplasschenDepartment of Special Needs Education, Ghent University, Belgium.
Deborah L SinclairDepartment of Special Needs Education, Ghent University, Belgium.
Martin M BalukuDepartment of Educational, Social and Organizational Psychology, Makerere University, Kampala, Uganda.
Raymond F OdokonyeroDepartment of Psychiatry, Makerere University, Kampala, Uganda.
Charles P NamisiDepartment of Epidemiology and Biostatistics, Makerere University, Kampala, Uganda.
John MukisaDepartment of Epidemiology and Biostatistics, Makerere University, Kampala, Uganda.
Ross G WhiteSchool of Psychology, Queens University, Belfast, Northern Ireland.
Carol S CamlinDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA.

Funding

Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in UgandaD43TW011304 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI Carol Suzanne Camlin, MOSES Robert KAMYA · 2019 to 2026
$2.2M
Mentoring Clinical Investigators in Patient Oriented Research on Human Mobility and HIVK24MH126808 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CAMLIN, CAROL SUZANNE · 2021 to 2025
$827k
FIC NIH HHS D43 TW011304NIMH NIH HHS K24 MH126808
6 · The paper itself

Abstract

Adherence to antiretroviral therapy (ART) is lower in adolescents with HIV (AWH) than in any other age group, partly due to self-regulatory challenges during development. Mindfulness and acceptance training have been shown to support psychological flexibility, a self-regulatory skill that potentially improves adolescent adherence to medication. We assessed the effect of weekly group-based mindfulness and acceptance training sessions on ART adherence among older adolescents (15-19 years) in Kampala, Uganda. One hundred and twenty-two AWH (median age 17, range 15-19 years, 57% female) receiving care at a public health facility in Kampala were randomized 1:1 to receive 4 weekly 90-min group sessions facilitated by experienced trainers or standard-of-care ART services. The training involved (Session 1) clarifying values, (Session 2) skillfully relating to thoughts, (Session 3) allowing and becoming aware of experiences non-judgmentally, and (Session 4) exploring life through trial and error. At baseline, postintervention, and 3-month follow-up, psychological flexibility was measured using the Avoidance and Fusion Questionnaire for Youth (AFQ-Y8), and self-reported ART adherence was assessed using the Morisky Medication Adherence Scale (MMAS-8). At baseline, the intervention and standard-of-care arms had similar psychological flexibility (AFQ-Y8 score:15.45 ± 0.82; 15.74 ± 0.84) and ART adherence (MMAS-8 score: 5.32 ± 0.24; 5.13 ± 0.23). Retention through the study was moderate (71%). Completion of mindfulness and acceptance training was associated with a significant reduction in psychological inflexibility at the 3-month follow-up (AFQ-Y8 score: 12.63 ± 1.06; 14.05 ± 1.07,

Indexed as

HIV InfectionsMindfulnessAdolescentAdultAwarenessFemaleHumansMalePatient ComplianceUgandaYoung Adultadherencehealth outcomesHIVmental healthmindfulnesspsychological flexibility

Identifiers

PMID38446992
PMCPMC10919136

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.