Evidence map›Paper›PMID 38446868›Full record

ArticlePsychological science2024

Multivariate Assessment of Inhibitory Control in Youth: Links With Psychopathology and Brain Function.

Elise M Cardinale, Jessica Bezek, Olivia Siegal, Gabrielle F Freitag, Anni Subar, Parmis Khosravi, Ajitha Mallidi, Olivia Peterson, Isaac Morales, Simone P Haller and 7 more

Open access · greenAbstract read
In one paragraph

Article in Psychological science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Bidirectional association between irritability and executive function in youth from late childhood to early adolescence: Between- and within-person effects.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
  2. Article
  3. Model-based analysis of stop-signal data reveals robust neural and clinical correlates of evidence accumulation but not inhibition.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Article
  6. Targeting inhibitory control in youth irritability: challenges and opportunities.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Elise M CardinaleDepartment of Psychology, The Catholic University of America.ORCID 0000-0002-5117-6124
Jessica BezekDepartment of Psychology, University of Michigan.
Olivia SiegalEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Gabrielle F FreitagEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Anni SubarDepartment of Child and Adolescent Psychiatry, New York University Grossman School of Medicine.
Parmis KhosraviEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Ajitha MallidiEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Olivia PetersonEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Isaac MoralesEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Simone P HallerEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Courtney FilippiDepartment of Psychology, University of Denver.
Kyunghun LeeEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Melissa A BrotmanEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Ellen LeibenluftEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Daniel S PineEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
Julia O LinkeDepartment of Psychology, University of Freiburg.
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health, Bethesda, MD.
National Institute of Mental Health · USNew York University · USUniversity of Denver · USUniversity of Freiburg · DEUniversity of Michigan · US

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
NIH HHS NCT00006177NIH HHS NCT00018057NIH HHS NCT00025935NIH HHS NCT02531893NIMH NIH HHS ZIAMH002781
6 · The paper itself

Abstract

Inhibitory control is central to many theories of cognitive and brain development, and impairments in inhibitory control are posited to underlie developmental psychopathology. In this study, we tested the possibility of shared versus unique associations between inhibitory control and three common symptom dimensions in youth psychopathology: attention-deficit/hyperactivity disorder (ADHD), anxiety, and irritability. We quantified inhibitory control using four different experimental tasks to estimate a latent variable in 246 youth (8-18 years old) with varying symptom types and levels. Participants were recruited from the Washington, D.C., metro region. Results of structural equation modeling integrating a bifactor model of psychopathology revealed that inhibitory control predicted a shared or general psychopathology dimension, but not ADHD-specific, anxiety-specific, or irritability-specific dimensions. Inhibitory control also showed a significant, selective association with global efficiency in a frontoparietal control network delineated during resting-state functional magnetic resonance imaging. These results support performance-based inhibitory control linked to resting-state brain function as an important predictor of comorbidity in youth psychopathology.

Indexed as

Attention Deficit Disorder with HyperactivityPsychopathologyAdolescentAnxietyBrainChildHumansMagnetic Resonance Imagingchildhood psychopathologyglobal efficiencyinhibitory controllatent factoropen dataresting-state functional magnetic resonance imaging

Identifiers

PMID38446868
PMCPMC11145514
OpenAlexW4392502514

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.