ArticlePloS one2024
Associations between adiposity measures and depression and well-being scores: A cross-sectional analysis of middle- to older-aged adults.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Similar Adiposity Improvements but Different Eating Behavior and Mental Health Responses in Men and Women: A 12-Week Exploratory Study.Nutrients · 2026Article
- Plant-based dietary indices and mental health: a cross-sectional study of a middle- to older-aged population.European journal of nutrition · 2026Article
- Gait Biomechanics Across BMI Categories in Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Emotional and Uncontrolled Eating Mediate the Well-Being-Adiposity Relationship in Women but Not in Men.Nutrients · 2025Article
- Neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) mediates the relationship between abdominal fat index and depression in a cross-sectional study.BMC psychiatry · 2025Article
- Article
- Tobacco smoking and the risk of eating behaviors and depression among Palestinian female university students.Discover mental health · 2025Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity and mental health are significant global health concerns. Evidence has linked increased adiposity with depression and well-being; however, there is limited documented evidence in Ireland. Research also suggests lifestyle factors and disease conditions to be related to mental health. These may modulate relationships between adiposity and depression and well-being.
methodsThis was a cross-sectional study of 1,821 men and women aged 46-73 years, randomly selected from a large primary care centre. Depression and well-being were assessed using the 20-item Centre for Epidemiologic Studies Depression Scale (CES-D) and the World Health Organization-Five (WHO-5) Well-Being Index. Linear regression analyses were performed to examine relationships between mental health scores (dependent variable) and adiposity (independent variable) defined using body mass index (BMI) and waist-height ratio while adjusting for demographic characteristics, lifestyle factors and disease conditions.
resultsBMI and waist-height ratio had a significant positive association with depression scores and a significant inverse association with well-being scores in males and females. These associations were maintained following adjustment for demographic variables and lifestyle factors. In final models where disease conditions were adjusted for, BMI (β = 0.743, p < .001) and waist-height ratio (β = 0.719, p < .001) associations with the CES-D score remained significant. In stratified analyses, relationships between measures of adiposity and depression were found to be stronger in females (BMI: β = 0.806, p = .007; waist-height ratio: β = 0.768, p = .01) than males (BMI: β = 0.573, p = .049; waist-height ratio: β = 0.593, p = .044) but no effect modification was identified.
conclusionsThese findings suggest that increased adiposity is significantly associated with poorer mental health, independent of lifestyle factors and disease conditions. Targeted interventions for reducing depression should include better population-level weight management measures.
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Registered trials
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