Evidence map›Paper›PMID 38446259›Full record

ArticlePediatric surgery international2024

Efforts to improve outcomes among neonates with complex intestinal atresia: a single-center low-income country experience.

Innocent Okello, Caroline Q Stephens, Nasser Kakembo, Phyllis Kisa, Stella Nimanya, Ava Yap, Anne S Wesonga, Rovine Naluyimbazi, Peter Kayima, Yasin Ssewanyana and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Fetal MRI: abdominal cystic lesions.Insights into imaging · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Innocent OkelloMulago National Referral Hospital, Kampala, Uganda.
Caroline Q StephensDepartment of Surgery, Center for Health Equity and Anesthesia, University of California - San Francisco, San Francisco, USA. caroline.stephens2@ucsf.edu.
Nasser KakemboMakerere University College of Health Sciences, Kampala, Uganda.
Phyllis KisaMakerere University College of Health Sciences, Kampala, Uganda.
Stella NimanyaMulago National Referral Hospital, Kampala, Uganda.
Ava YapDepartment of Surgery, Center for Health Equity and Anesthesia, University of California - San Francisco, San Francisco, USA.
Anne S WesongaMulago National Referral Hospital, Kampala, Uganda.
Rovine NaluyimbaziMulago National Referral Hospital, Kampala, Uganda.
Peter KayimaMulago National Referral Hospital, Kampala, Uganda.
Yasin SsewanyanaMulago National Referral Hospital, Kampala, Uganda.
Doruk OzgedizDepartment of Surgery, Center for Health Equity and Anesthesia, University of California - San Francisco, San Francisco, USA.
John SekabiraMulago National Referral Hospital, Kampala, Uganda.
Mulago Hospital · UGUniversity of California, San Francisco · USMakerere University · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIntestinal obstruction caused by intestinal atresia is a surgical emergency in newborns. Outcomes for the jejunal ileal atresia (JIA), the most common subtype of atresia in low-income countries (LIC), are poor. We sought to assess the impact of utilizing the Bishop-Koop (BK) approach to JIA in improving outcomes.

methodsA retrospective cohort study was performed on children with complex JIA (Type 2-4) treated at our national referral hospital from 1/2018 to 12/2022. BK was regularly used starting 1/1/2021, and outcomes between 1/2021 and 12/2022 were compared to those between 1/2018 and 12/2020. Statistical significance was set at p < 0.05.

resultsA total of 122 neonates presented with JIA in 1/2018-12/2022, 83 of whom were treated for complex JIA. A significant decrease (p = 0.03) was noted in patient mortality in 2021 and 2022 (n = 33, 45.5% mortality) compared to 2018-2020 (n = 35, 71.4% mortality). This translated to a risk reduction of 0.64 (95% CI 0.41-0.98) with the increased use of BK.

conclusionIncreased use of BK anastomoses with early enteral nutrition and decreased use of primary anastomosis improves outcomes for neonates with severe JIA in LIC settings. Implementing this surgical approach in LICs may help address the disparities in outcomes for children with JIA.

Indexed as

Intestinal AtresiaChildHumansIleumInfant, NewbornIntestine, SmallJejunumRetrospective StudiesCongenital abnormalitiesDisparitiesGlobal healthInfantIntestinal atresiaNewborn

Identifiers

PMID38446259
PMCPMC10917857
OpenAlexW4392519241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.