Evidence map›Paper›PMID 38446249›Full record

ArticleEJNMMI research2024

Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [

Obada M Alzghool, Richard Aarnio, Jatta S Helin, Saara Wahlroos, Thomas Keller, Markus Matilainen, Junel Solis, Jonathan J Danon, Michael Kassiou, Anniina Snellman and 3 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Obada M AlzghoolPET Preclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6 A, 20520, Turku, Finland. obalzg@utu.fi.ORCID http://orcid.org/0000-0002-6166-4957
Richard AarnioPET Preclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6 A, 20520, Turku, Finland.
Jatta S HelinPET Preclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6 A, 20520, Turku, Finland.
Saara WahlroosRadiopharmaceutical Chemistry Laboratory, Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Thomas KellerRadiopharmaceutical Chemistry Laboratory, Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Markus MatilainenTurku University Hospital, Turku PET Centre, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Junel SolisTurku BioImaging, Åbo Akademi University and University of Turku, Turku, Finland.
Jonathan J DanonSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Michael KassiouSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Anniina SnellmanPET Preclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6 A, 20520, Turku, Finland.
Olof SolinRadiopharmaceutical Chemistry Laboratory, Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Juha O RinneTurku University Hospital, Turku PET Centre, Kiinamyllynkatu 4-8, 20520, Turku, Finland.
Merja Haaparanta-SolinPET Preclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6 A, 20520, Turku, Finland.
University of Turku · FIÅbo Akademi University · FIThe University of Sydney · AUTurku University Hospital · FITurku PET Centre · FI

Funding

Academy of Finland 310962Finnish governmental research funding 11133
6 · The paper itself

Abstract

backgroundP2X7 receptor has emerged as a potentially superior PET imaging marker to TSPO, the gold standard for imaging glial reactivity. [

resultsLongitudinal change in [

conclusions[

Indexed as

[11C]SMW139[18F]F-DPAAlzheimer’s diseaseAPP/PS1-21MicrogliaP2X7P2Y12Positron emission tomographyTSPO

Identifiers

PMID38446249
PMCPMC10917722
OpenAlexW4392516764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.