ArticleClinical research in cardiology : official journal of the German Cardiac Society2024
Incidence and predictors of left atrial thrombus in patients with atrial fibrillation under anticoagulation therapy.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- NovelBiomedicines · 2026Article
- Rare TruncatingGenes · 2026Article
- Integrating left atrial appendage morphology and lipoprotein(a) improves thrombus risk stratification in atrial fibrillation: a retrospective cohort study.International journal of cardiology. Heart & vasculature · 2026Article
- Association between complete blood cell count-derived inflammatory indices and left atrial thrombus in patients with nonvalvular atrial fibrillation: a cross-sectional study.Frontiers in medicine · 2026Article
- Discovery ofDiagnostics (Basel, Switzerland) · 2025Article
- Spontaneous echo contrast in the left atrial appendage is linked to a higher risk of thromboembolic events and mortality in patients with atrial fibrillation.International journal of cardiology. Heart & vasculature · 2025Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundLeft atrial thrombus (LAT) formation is associated with thromboembolic events.
objectiveTo investigate the incidence and associated factors of LAT in patients with atrial fibrillation (AF) who had been receiving anticoagulation therapy for more than 4 weeks, and to develop a prediction model using clinical and echocardiographic features.
methodsMedical records of 1,122 patients with AF (mean age, 59.4 ± 11.0 years, 58.3% male) who were on anticoagulation more than 4 weeks and underwent transesophageal echocardiography (TEE) were evaluated. The main outcome was the presence of LAT on TEE.
resultsWarfarin and non-vitamin K oral anticoagulants were used in 74.4% and 25.6% of the patients at the time of examination, respectively. LAT was present in 60 patients (5.3%). Presence of LAT on TEE was associated with age ≥ 75 years (odds ratio [OR] 2.13 [95% confidence interval, 0.94-4.58]), persistent/permanent AF (OR 2.61 [1.42-4.93]), CHA
conclusionsLAT was present in a considerable number of patients who were already receiving anticoagulation therapy. A prediction model that combines clinical and echocardiographic predictors could be useful in distinguishing patients who require imaging evaluations before left atrial intervention.
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