Evidence map›Paper›PMID 38446051›Full record

ArticleACS infectious diseases2024

Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant

Jonathan M Turner, Caleb M Stratton, Sandeepchowdary Bala, Maria Cardenas Alvarez, Robert A Nicholas, Christopher Davies

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jonathan M TurnerDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425, United States.ORCID 0000-0002-6162-3063
Caleb M StrattonDepartment of Biochemistry and Molecular Biology, University of South Alabama, Mobile, Alabama 36688, United States.
Sandeepchowdary BalaDepartment of Biochemistry and Molecular Biology, University of South Alabama, Mobile, Alabama 36688, United States.
Maria Cardenas AlvarezDepartments of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0003-3061-1518
Robert A NicholasDepartments of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0003-2507-8974
Christopher DaviesDepartment of Biochemistry and Molecular Biology, University of South Alabama, Mobile, Alabama 36688, United States.ORCID 0000-0002-6687-4064
University of South Alabama · USUniversity of North Carolina at Chapel Hill · USMedical University of South Carolina · US

Funding

The Atlantic Coast Sexually Transmitted Infection Cooperative Research Center (ACU19AI113170 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI JERSE, ANN E. · 2014 to 2018
$6.9M
Supplement to Molecular Targets in Peptidoglycan SynthesisR01GM066861 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DAVIES, CHRISTOPHER · 2003 to 2019
$5.4M
Molecular mechanism of cephalosporin resistance of N. gonorrhoeae conferred by mutated PBP2R01AI164794 · NIAID · UNIVERSITY OF SOUTH ALABAMA · PI Christopher Davies · 2022 to 2026
$3.5M
NIAID NIH HHS R01 AI164794NIAID NIH HHS U19 AI113170NIGMS NIH HHS R01 GM066861
6 · The paper itself

Abstract

Effective treatment of gonorrhea is threatened by the increasing prevalence of

Indexed as

CeftriaxoneGonorrheabeta-LactamsCefoperazoneCephalosporinsHumansNeisseria gonorrhoeaePenicillin-Binding ProteinsPiperacillinbeta-LactamsCefoperazoneCeftriaxoneCephalosporinsPenicillin-Binding ProteinsPiperacillinantimicrobial resistanceNeisseria gonorrhoeaepenicillin-binding protein 2β-lactams

Identifiers

PMID38446051
PMCPMC11812267
OpenAlexW4392519374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.