ArticleRadiology. Artificial intelligence2024
Noninvasive Molecular Subtyping of Pediatric Low-Grade Glioma with Self-Supervised Transfer Learning.
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Article in Radiology. Artificial intelligence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
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Who cites it
24 citing papers in PubMed, 30 citations in OpenAlex.
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- Segmentation-free pretherapeutic assessment of BRAF-status in pediatric low-grade gliomas.Communications medicine · 2025Article
- Multiclass machine learning models for molecular subtype identification of pediatric low-grade glioma using bi-institutional MRIs for precision medicine.NPJ precision oncology · 2025Article
- Super-resolution deep learning reconstruction to evaluate lumbar spinal stenosis status on magnetic resonance myelography.Japanese journal of radiology · 2025Article
- Illuminating radiogenomic signatures in pediatric-type diffuse gliomas: insights into molecular, clinical, and imaging correlations. Part II: low-grade group.La Radiologia medica · 2025Review
- Integration of Multi-omics Data Based on Deep Learning for Subtyping of Low-Grade Glioma.Journal of molecular neuroscience : MN · 2025Article
- AI-Driven Innovations in Neuroradiology and Neurosurgery: Scoping Review of Current Evidence and Future Directions.Cancers · 2025Review
- Imaging Clusters of Pediatric Low-Grade Glioma Are Associated with Distinct Molecular Characteristics.AJNR. American journal of neuroradiology · 2025Article
- Large multimodality model fine-tuned for detecting breast and esophageal carcinomas on CT: a preliminary study.Japanese journal of radiology · 2025Article
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- Multimodal contrastive learning for enhanced explainability in pediatric brain tumor molecular diagnosis.Scientific reports · 2025Article
- Multimodal deep learning improves recurrence risk prediction in pediatric low-grade gliomas.Neuro-oncology · 2025Article
- A review of deep learning for brain tumor analysis in MRI.NPJ precision oncology · 2025Review
- Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.Nature communications · 2025Article
- Towards consistency in pediatric brain tumor measurements: Challenges, solutions, and the role of artificial intelligence-based segmentation.Neuro-oncology · 2024Review
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Authors and funding
21 authors at 1 institution in 1 country.
Divyanshu Tak *From the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0009-0003-4183-209X
Zezhong Ye *From the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0003-0369-7432
Anna ZapaischykovaFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0001-6860-9160
Yining ZhaFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0009-0000-7653-3223
Aidan BoydFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0001-9756-0570
Sridhar VajapeyamFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-1782-1919
Rishi ChopraFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0009-0006-3247-1204
Hasaan HayatFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0001-9294-1016
Sanjay P PrabhuFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0003-0871-115X
Kevin X LiuFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0003-2071-5137
Hesham ElhalawaniFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Ali NabavizadehFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-0380-4552
Ariana FamiliarFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-9315-8653
Adam C ResnickFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Sabine MuellerFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Hugo J W L AertsFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Pratiti BandopadhayayFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
Keith L LigonFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-7733-600X
Daphne A Haas-KoganFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-2378-4800
Tina Y PoussaintFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-0814-0791
Benjamin H KannFrom the Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Mass (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., H.J.W.L.A., B.H.K.); Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115 (D.T., Z.Y., A.Z., Y.Z., A.B., R.C., H.H., K.X.L., H.E., H.J.W.L.A., D.A.H.K., B.H.K.); Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Mass (S.V., S.P.P., T.Y.P.); Center for Data-Driven Discovery in Biomedicine (A.N., A.F.) and Department of Neurosurgery (A.F., A.C.R.), Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (A.N.); Departments of Neurology, Pediatrics, and Neurologic Surgery, University of California San Francisco, San Francisco, Calif (S.M.); Department of Radiology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (H.J.W.L.A.); Department of Radiology and Nuclear Medicine, CalifRIM & GROW, Maastricht University, Maastricht, the Netherlands (H.J.W.L.A.); and Department of Pediatric Oncology (P.B.) and Department of Pathology (K.L.L.), Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Mass.ORCID 0000-0002-4313-2754
Brigham and Women's Hospital · US
Funding
Targeting the Vasular SystemP50CA165962 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Benjamin Harris Kann · 2013 to 2026
$33.5MThe Boston Lung Cancer Survival CohortU01CA209414 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI David C Christiani · 2017 to 2026
$12.2MShared Resource Core 2: Clinical Artificial Intelligence CoreU54CA274516 · NCI · DANA-FARBER CANCER INST · PI DAPHNE A. HAAS-KOGAN · 2023 to 2026
$8.1MQuantitative Radiomics System Decoding the Tumor PhenotypeU24CA194354 · NCI · DANA-FARBER CANCER INST · PI AERTS, HUGO, QUACKENBUSH, JOHN · 2015 to 2019
$3.5MGenotype and Imaging Phenotype Biomarkers in Lung CancerU01CA190234 · NCI · DANA-FARBER CANCER INST · PI AERTS, HUGO, QUACKENBUSH, JOHN · 2015 to 2019
$3.3MDevelopment of an artificial intelligence-driven, imaging-based platform for pretreatment identification of extranodal extension in head and neck cancerK08DE030216 · NIDCR · BRIGHAM AND WOMEN'S HOSPITAL · PI KANN, BENJAMIN HARRIS · 2021 to 2025
$841kNCI NIH HHS P50 CA165962NCI NIH HHS U01 CA190234NCI NIH HHS U01 CA209414NCI NIH HHS U24 CA194354NCI NIH HHS U54 CA274516NIDCR NIH HHS K08 DE030216
Abstract
Purpose To develop and externally test a scan-to-prediction deep learning pipeline for noninvasive, MRI-based
Indexed as
Brain NeoplasmsGliomaChildFemaleHumansMachine LearningMaleProto-Oncogene Proteins B-rafRetrospective StudiesProto-Oncogene Proteins B-rafBrain/Brain StemCNSConvolutional Neural Network (CNN)DiagnosisFeature DetectionMRIOncologyPediatricsSupervised LearningTransfer Learning
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.