Evidence map›Paper›PMID 38446031›Full record

ArticleeLife2024

Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in

Benson Otarigho, Anna Frances Butts, Alejandro Aballay

Open access · goldAbstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benson OtarighoDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, United States.ORCID https://orcid.org/0000-0001-6347-3831
Anna Frances ButtsDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, United States.
Alejandro AballayDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, United States.ORCID https://orcid.org/0000-0002-5975-3352
The University of Texas MD Anderson Cancer Center · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
C. elegans to study organismal control of recovery from bacterial infectionsR01AI117911 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI ABALLAY, ALEJANDRO · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI117911NIH HHS AI117911NIH HHS GM0709077NIH HHS P40 OD010440
6 · The paper itself

Abstract

The survival of hosts during infections relies on their ability to mount effective molecular and behavioral immune responses. Despite extensive research on these defense strategies in various species, including the model organism

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsBasic Helix-Loop-Helix ProteinsChemotaxisGATA Transcription FactorsImmunityIntestinesReceptors, G-Protein-CoupledSensory Receptor CellsBasic Helix-Loop-Helix ProteinsCaenorhabditis elegans ProteinsELT-2 protein, C elegansGATA Transcription FactorsHLH-30 protein, C elegansnpr-15 protein, C elegansReceptors, G-Protein-Coupledavoidance behaviorC. elegansG-protein-coupled receptorsimmunityimmunologyinflammationneuropeptidesneuroscience

Identifiers

PMID38446031
PMCPMC10942643
OpenAlexW4387333879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.