Evidence map›Paper›PMID 38445989›Full record

ArticleACS synthetic biology2024

Genome Engineering by RNA-Guided Transposition for

Sergio Arévalo, Daniel Pérez Rico, Dolores Abarca, Laura W Dijkhuizen, Cristina Sarasa-Buisan, Peter Lindblad, Enrique Flores, Sandra Nierzwicki-Bauer, Henriette Schluepmann

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Sergio ArévaloBiology Department, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Daniel Pérez RicoBiology Department, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Dolores AbarcaBiology Department, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Laura W DijkhuizenBiology Department, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0000-0002-4628-7671
Cristina Sarasa-BuisanInstituto de Bioquímica Vegetal y Fotosíntesis, CSIC and Universidad de Sevilla, Avenida Americo Vespucio 49, Sevilla 41092, Spain.
Peter LindbladMicrobial Chemistry, Department of Chemistry-Ångström Laboratory, Uppsala University, Lägerhyddsvägen 1, 751 20 Uppsala, Sweden.ORCID 0000-0001-7256-0275
Enrique FloresInstituto de Bioquímica Vegetal y Fotosíntesis, CSIC and Universidad de Sevilla, Avenida Americo Vespucio 49, Sevilla 41092, Spain.
Sandra Nierzwicki-BauerDepartment of Biological Sciences, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180-3590, United States.
Henriette SchluepmannBiology Department, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.ORCID 0000-0001-6171-3029
Utrecht University · NLInstituto de Bioquímica Vegetal y Fotosíntesis · ESUppsala University · SERensselaer Polytechnic Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In genome engineering, the integration of incoming DNA has been dependent on enzymes produced by dividing cells, which has been a bottleneck toward increasing DNA insertion frequencies and accuracy. Recently, RNA-guided transposition with CRISPR-associated transposase (CAST) was reported as highly effective and specific in

Indexed as

AnabaenaCyanobacteriaDNADNA Transposable ElementsEscherichia coliHumansPlasmidsRNARNA, Guide, CRISPR-Cas SystemsDNADNA Transposable ElementsRNARNA, Guide, CRISPR-Cas SystemsAnabaenaCRISPR-associated transposon (CAST)de novo genome assemblygenome engineeringminion sequencingRNA-guided transposition

Identifiers

PMID38445989
PMCPMC10949235
OpenAlexW4392519069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.