Evidence map›Paper›PMID 38445903›Full record

ArticleApplied and environmental microbiology2024

Composting reduces the risks of resistome in beef cattle manure at the transcriptional level.

Yuepeng Sun, Zachery R Staley, Bryan Woodbury, Jean-Jack Riethoven, Xu Li

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuepeng Sun *School of Ecology and Environment, Inner Mongolia University, Hohhot, China.ORCID 0000-0002-5245-1255
Zachery R Staley *Department of Civil and Environmental Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Bryan WoodburyUSDA-ARS U.S. Meat Animal Research Center, Clay Center, Clay Center, Nebraska, USA.
Jean-Jack RiethovenCenter for Biotechnology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
Xu LiDepartment of Civil and Environmental Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0000-0002-1006-3027

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Apar Kishor Ganti · 1985 to 2026
$55.0M
UNMC Histology/Imaging and Creighton University Imaging Core FacilityP30GM110768 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SMITH, SHELLEY D · 2014 to 2018
$5.1M
NCI NIH HHS P30 CA036727NIGMS NIH HHS P20 GM103427NIGMS NIH HHS P30 GM110768
6 · The paper itself

Abstract

Transcriptomic evidence is needed to determine whether composting is more effective than conventional stockpiling in mitigating the risk of resistome in livestock manure. The objective of this study is to compare composting and stockpiling for their effectiveness in reducing the risk of antibiotic resistance in beef cattle manure. Samples collected from the center and the surface of full-size manure stockpiling and composting piles were subject to metagenomic and metatranscriptomic analyses. While the distinctions in resistome between stockpiled and composted manure were not evident at the DNA level, the advantages of composting over stockpiling were evident at the transcriptomic level in terms of the abundance of antibiotic resistance genes (ARGs), the number of ARG subtypes, and the prevalence of high-risk ARGs (i.e., mobile ARGs associated with zoonotic pathogens). DNA and transcript contigs show that the pathogen hosts of high-risk ARGs included

Indexed as

CompostingManureAnimalsAnti-Bacterial AgentsCattleDNADrug Resistance, MicrobialGenes, BacterialAnti-Bacterial AgentsDNAManureantibiotic resistance genesbeef cattle manurecompostingmetagenomicsmetatranscriptomicsresistomestockpiling

Identifiers

PMID38445903
PMCPMC11022583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.