Evidence map›Paper›PMID 38445705›Full record

ArticleJournal of microscopy2024

The rise of data-driven microscopy powered by machine learning.

Leonor Morgado, Estibaliz Gómez-de-Mariscal, Hannah S Heil, Ricardo Henriques

Open access · hybridAbstract read
In one paragraph

Article in Journal of microscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Advanced Microscopy Techniques.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Ultrafast tomograms in a flash.Science advances · 2025
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Leonor MorgadoOptical Cell Biology, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID https://orcid.org/0000-0003-4510-8456
Estibaliz Gómez-de-MariscalOptical Cell Biology, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID https://orcid.org/0000-0003-2082-3277
Hannah S HeilOptical Cell Biology, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID https://orcid.org/0000-0003-4279-7022
Ricardo HenriquesOptical Cell Biology, Instituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID https://orcid.org/0000-0002-2043-5234
Instituto Gulbenkian de Ciência · PTMRC Laboratory for Molecular Cell Biology · GB

Funding

AbbelightCalouste Gulbenkian FoundationChan Zuckerberg Initiative NP2-0000000085Chan Zuckerberg Initiative vpi-0000000044European Molecular Biology Organization ALTF 174-2022European Molecular Biology Organization ALTF 499-2021European Molecular Biology Organization EMBO-2020-IG-4734European Research Council 101001332European Union 101057970-AI4LIFEEuropean Union 101099654-RT-SuperESFundação para a Ciência e a Tecnologia CEECIND/01480/2021Instituto Gulbenkian de CiênciaLS4FUTURE Associated Laboratory LA/P/0087/2020
6 · The paper itself

Abstract

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field of view and phototoxicity. To overcome these limitations, data-driven microscopes incorporate feedback loops between data acquisition and analysis. This review overviews how machine learning enables automated image analysis to optimise microscopy in real time. We first introduce key data-driven microscopy concepts and machine learning methods relevant to microscopy image analysis. Subsequently, we highlight pioneering works and recent advances in integrating machine learning into microscopy acquisition workflows, including optimising illumination, switching modalities and acquisition rates, and triggering targeted experiments. We then discuss the remaining challenges and future outlook. Overall, intelligent microscopes that can sense, analyse and adapt promise to transform optical imaging by opening new experimental possibilities.

Indexed as

data‐drivenimage analysismachine learningreactive microscopy

Identifiers

PMID38445705
PMCPMC7618355
OpenAlexW4392508101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.