Evidence map›Paper›PMID 38444864›Full record

ReviewResuscitation plus2024

Wolf Creek XVII Part 6: Physiology-Guided CPR.

Janet Bray, Tom Rea, Sam Parnia, Ryan W Morgan, Lars Wik, Robert Sutton

Open access · goldAbstract readReview
In one paragraph

Review in Resuscitation plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Janet BraySchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Tom ReaEmergency Medical Services Division of Public Health - Seattle & King County, United States, Department of Medicine, University of Washington, United States.
Sam ParniaNew York University Grossman School of Medicine, New York, New York, United States.
Ryan W MorganChildren's Hospital of Philadelphia, Philadelphia, United States.
Lars WikNational Service of Competence for Prehospital Acute Medicine (NAKOS), Department of Air Ambulance, Oslo, Norway.
Robert SuttonChildren's Hospital of Philadelphia, Philadelphia, United States.
Children's Hospital of Philadelphia · USCurtin University · AUNew York University · USOslo University Hospital · NOPublic Health – Seattle & King County · US

Funding

Transforming Resuscitation through Artificial INtelligence (TRAIN Study)R01HL169323 · NHLBI · UNIVERSITY OF WASHINGTON · PI THOMAS D REA · 2023 to 2026
$2.7M
NHLBI NIH HHS R01 HL169323
6 · The paper itself

Abstract

Introduction: Physiology-guided cardiopulmonary resuscitation (CPR) offers the potential to optimize resuscitation and enable early prognosis. Methods: Physiology-Guided CPR was one of six focus topic for the Wolf Creek XVII Conference held on June 14-17, 2023 in Ann Arbor, Michigan, USA. International thought leaders and scientists in the field of cardiac arrest resuscitation from academia and industry were invited. Participants submitted via online survey knowledge gaps, barriers to translation and research priorities for each focus topic. Expert panels used the survey results and their own perspectives and insights to create and present a preliminary unranked list for each category, which was then debated, revised and ranked by all attendees to identify the top 5 for each category. Results: Top knowledge gaps include identifying optimal strategies for the evaluation of physiology-guided CPR and the optimal values for existing patients using patient outcomes. The main barriers to translation are the limited usability outside of critical care environments and the training and equipment required for monitoring. The top research priorities are the development of clinically feasible and reliable methods to continuously and non-invasively monitor physiology during CPR and prospective human studies proving targeting parameters during CPR improves outcomes. Conclusion: Physiology-guided CPR has the potential to provide individualized resuscitation and move away from a one-size-fits-all approach. Current understanding is limited, and clinical trials are lacking. Future developments need to consider the clinical application and applicability of measurement to all healthcare settings. Therefore, clinical trials using physiology-guided CPR for individualisation of resuscitation efforts are needed.

Indexed as

Heart arrestPhysiology-guided CPRResuscitation

Identifiers

PMID38444864
PMCPMC10912729
OpenAlexW4392338483

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.