Evidence map›Paper›PMID 38444817›Full record

ArticleOpen forum infectious diseases2024

An Emergent Change in Epidemiologic and Microbiological Characteristics of Bloodstream Infections in Adults With Febrile Neutropenia Resulting From Chemotherapy for Acute Leukemia and Lymphoma at Reference Centers in Chile, Ecuador, and Peru.

Ricardo Rabagliati, Grace Salazar, Giancarlo Pérez-Lazo, Maria Paz Iturrieta, Diana Portillo, Carmen Soria-Segarra, María José Ojeda, Jimena Flores, Margarita Galarza, Roxana Sandoval-Ahumada and 4 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Management of Febrile Neutropenia in a Tropical Country.Hematology, transfusion and cell therapy · 2024
    Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Ricardo RabagliatiDepartamento de Enfermedades Infecciosas del Adulto, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-0574-8312
Grace SalazarHospital de Especialidades Eugenio Espejo, Quito, Ecuador.
Giancarlo Pérez-LazoHospital Nacional Guillermo Almenara Irigoyen, EsSalud, Lima, Perú.
Maria Paz IturrietaHospital Sótero del Río, Santiago, Chile.
Diana PortilloInstituto Nacional de Enfermedades Neoplásicas, Lima, Perú.
Carmen Soria-SegarraUniversidad Católica Santiago de Guayaquil, Guayaquil, Ecuador.
María José OjedaDepartamento de Enfermedades Infecciosas del Adulto, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jimena FloresDepartamento de Enfermedades Infecciosas del Adulto, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Margarita GalarzaLaboratorio Microbiología, Hospital Eugenio Espejo, Quito, Ecuador.
Roxana Sandoval-AhumadaHospital Nacional Guillermo Almenara Irigoyen, EsSalud, Lima, Perú.
Pablo Cartes AguileraLaboratorio Microbiología, Hospital Sótero del Río, Santiago, Chile.
Lady DimitrakisLaboratorio Microbiología, Sociedad Lucha contra el Cáncer SOLCA, Guayaquil, Ecuador.
Fabiola Avelga ReinosoLaboratorio Microbiología, Sociedad Lucha contra el Cáncer SOLCA, Guayaquil, Ecuador.
Patricia GarciaDepartamento de Laboratorios Clínicos, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pontificia Universidad Católica de Chile · CLComplejo Asistencial Sótero del Río · CLHospital Base Guillermo Almenara Irigoyen · PEInstituto Nacional de Enfermedades Neoplásicas · PEUniversidad Católica de Santiago de Guayaquil · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Febrile neutropenia is a life-threatening condition commonly observed in patients with hematologic malignancies. The aim of this article is to provide updated knowledge about bloodstream infections in febrile neutropenia episodes within the Andean region of Latin America. Method: This retrospective study was based in 6 hospitals in Chile, Ecuador, and Peru and included adult patients with acute leukemia or lymphoma and febrile neutropenia between January 2019 and December 2020. Results: Of the 416 febrile neutropenia episodes, 38.7% had a bloodstream infection, 86% of which were caused by gram-negative rods, with Conclusions: Considering the high rates of bacteria-resistant infection and 30-day mortality, it is imperative to establish strategies that reduce the frequency of bloodstream infections, increasing early identification of patients at higher risks of multidrug bacteria resistance, and updating existing empirical antibiotic recommendations.

Indexed as

bloodstream infectionfebrile neutropeniagram-negative rodsmultidrug resistance

Identifiers

PMID38444817
PMCPMC10913838
OpenAlexW4391452047

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.