Evidence map›Paper›PMID 38444426›Full record

ArticleThe Journal of clinical and aesthetic dermatology2024

Gene Expression Analysis of a Topical Serum Comprised of Plant-based Adaptogens Developed to Support Homeostasis and Skin Quality.

Zoe Diana Draelos, Pearl E Grimes, Jacqueline Watchmaker, Diane B Nelson

Open access · greenAbstract read
In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Zoe Diana DraelosDr. Draelos is with Dermatology Consulting Services PLLC in High Point, North Carolina.
Pearl E GrimesDr Grimes is with The Grimes Center of Medical and Aesthetic Dermatology and the Vitiligo and Pigmentation Institute of Southern California in Los Angeles, California.
Jacqueline WatchmakerDr. Watchmaker is with Southwest Skin Specialists in Scottsdale, Arizona.
Diane B NelsonMs. Nelson is with Skinbetter Science, a Dermatological Beauty brand of L'Oréal USA, Inc. in Phoenix, Arizona.
Dermatology Consulting Services · USDermatology Specialists · USNelson Engineering (United States) · USVitiligo and Pigmentation Institute of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: A topical serum comprised of plant-based adaptogens was purposefully developed to support the ability of the skin to adapt and achieve balance. The study described herein evaluated changes in the expression of target genes related to skin homeostasis following topical exposure. Methods: Utilizing an Results: An 85 percent (FC=1.85) increase in expression of AhR vs. control occurred following exposure to MYS serum indicating enhanced support of cellular and epidermal homeostasis, and the skin barrier's response to stress. Statistically significant increases in expression occurred with Conclusion: Utilizing an

Indexed as

adaptogensanti-aging biomarkershomeostasisin vitro gene analysis

Identifiers

PMID38444426
PMCPMC10911264
OpenAlexW4394764544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.