Evidence map›Paper›PMID 38444421›Full record

ArticleFrontiers in medicine2024

Frequency of IDH1 mutation in adult-type diffuse astrocytic gliomas in a tertiary hospital in Kenya.

Samuel Gakinya, Anderson Mutuiri, Timothy Onyuma, Beverly Cheserem, Edwin Mogere

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samuel GakinyaDepartment of Pathology, Aga Khan University, Nairobi, Kenya.
Anderson MutuiriDepartment of Pathology, Aga Khan University, Nairobi, Kenya.
Timothy OnyumaKenyatta National Hospital, Nairobi, Kenya.
Beverly CheseremDepartment of Pathology, Aga Khan University, Nairobi, Kenya.
Edwin MogereDepartment of Pathology, Aga Khan University, Nairobi, Kenya.
Aga Khan University Nairobi · KEKenyatta National Hospital · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2021 WHO classification of gliomas has separated gliomas based on their IDH mutation status, reflecting differences in their pathogenesis and clinical characteristics. There is a paucity of data on the prevalence of IDH mutations in gliomas in this region. This study aimed to determine the frequency of the IDH1 mutation in adult-type diffuse astrocytic gliomas in a tertiary hospital in Kenya. Approximately half of the gliomas were positive for the IDH1 mutation, with a slight male predominance. Our study provides crucial insights into the frequency of IDH1 mutations in gliomas in Kenya.

Indexed as

AfricaastrocytomafrequencygliomaIDH1Kenya

Identifiers

PMID38444421
PMCPMC10913195
OpenAlexW4391941067

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.