Evidence map›Paper›PMID 38444415›Full record

ArticleFrontiers in medicine2024

Pulmonary inflammation decreases with ultra-protective ventilation in experimental ARDS under VV-ECMO: a positron emission tomography study.

Guillaume Deniel, François Dhelft, Sophie Lancelot, Maciej Orkisz, Emmanuel Roux, William Mouton, Nazim Benzerdjeb, Jean-Christophe Richard, Laurent Bitker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Guillaume DenielService de Médecine Intensive-Réanimation, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
François DhelftService de Médecine Intensive-Réanimation, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Sophie LancelotUniversité de Lyon, Université LYON 1, Lyon, France.
Maciej OrkiszUniv Lyon, Université Claude Bernard Lyon 1, INSA-Lyon, CNRS, Inserm, CREATIS UMR, Villeurbanne, France.
Emmanuel RouxUniv Lyon, Université Claude Bernard Lyon 1, INSA-Lyon, CNRS, Inserm, CREATIS UMR, Villeurbanne, France.
William MoutonLaboratoire Commun de Recherche Hospices Civils de Lyon/bioMérieux, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France.
Nazim BenzerdjebUniversité de Lyon, Université LYON 1, Lyon, France.
Jean-Christophe RichardService de Médecine Intensive-Réanimation, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Laurent BitkerService de Médecine Intensive-Réanimation, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Centre National de la Recherche Scientifique · FRHospices Civils de Lyon · FRCentre de Recherche en Acquisition et Traitement de l'Image pour la Santé · FRCentre Hospitalier Universitaire de Montpellier · FRInserm · FRLaboratoire d’Imagerie Biomédicale · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Experimentally, ultra-protective ventilation (UPV, tidal volumes [V Methods: ARDS was induced by tracheal instillation of chlorhydric acid in sedated and paralyzed animals under mechanical ventilation. Animals were randomized to receive either UPV (V Results: Five pigs were randomized to each study group. Arterial O Conclusion: In an experimental model of ARDS, 4 h of UPV strategy significantly decreased lung inflammation, in relation to the control of V

Indexed as

[11C](R)-PK11195acute respiratory distress syndromepositron emission tomographyquantitative computerized tomographyultra-protective ventilationventilator-induced lung injury

Identifiers

PMID38444415
PMCPMC10912585
OpenAlexW4391986613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.